Home > Research > NIBIB Intramural Labs > Laboratory of Bioengineering and Physical Science > LBPS Staff

E-mail this page

Alioscka Sousa, Ph.D. Research Fellow Supramolecular Structure and Function Laboratory of Bioengineering and Physical Science Bldg. 13, Rm. 3E73 Tel: 301-594-5346 Fax: 301-435-4699 E-mail: sousaali@mail.nih.gov

Research Interests

• Electron tomography
  • Determination of three-dimensional cellular ultrastructure
• Development of alternative methods in electron tomography
  • 3-D visualization of specific cellular proteins labeled with ultrasmall gold clusters
  • Reconstruction of micron-thick biological sections with nanometer resolution
• Quantitative imaging in the scanning transmission electron microscope
  • Mass measurement of supramolecular assemblies
• Quantitative characterization of nanoparticles used in nanomedicine
  • Measurement of mass, composition, and degree of homogeneity
• Correlative light-electron microscopy/tomography of biological structures, particularly using unconventional imaging modes in the electron microscope
  • Light microscopy/energy-filtering transmission electron microscopy/scanning transmission electron miscoscopy
• Image simulation in scanning transmission electron microscopy/tomography of biological specimens
  • Limits of detection
  • Optimization of imaging conditions