NIBIB-Supported Biomedical Technology Resource Centers
David D'ArgenioUniversity of Southern California
The Biomedical Simulations Resource (BMSR) in the Department of Biomedical Engineering at the University of Southern California is dedicated to the advancement of the state-of-the-art in biomedical modeling and simulation through Core and Collaborative Research projects, as well as the dissemination of this knowledge and related software through Service, Training and Dissemination activities aimed at the biomedical community at large. The BMSR includes four core research projects:Pharmacokinetic/Pharmacodynamic Systems Analysis David Z. D'Argenio, Ph.D., Co-DirectorNonlinear Modeling of Complex Biomedical Systems Vasilis Z. Marmarelis, Ph.D., Co-DirectorModeling of Autonomic, Metabolic and Vascular Control Interactions Michael C.K. Khoo, Ph.D., Co-InvestigatorNonlinear Modeling of the Hippocampus Theodore W. Berger, Ph.D., Co-InvestigatorFifteen Collaborative Research Projects serve as challenging test grounds for the Resource's methodologies and expertise. The BMSR's service activities include the development and distribution of four software packages (ADAPT, LYSIS, PNEUMA +amp; EONS).The Resource's Training and Dissemination activities include short courses, advanced workshops and the publication of associated research volumes.
Peter Van ZijlHugo W. Moser Res Inst Kennedy Krieger
This Resource is an interdepartmental and interdisciplinary laboratory combining facilities of the F.M. Kirby Research Center for Functional Brain Imaging at the Hugo Moser Research Institute at Kennedy Krieger (KKI) and the Center for Imaging Science (CIS) at Johns Hopkins University (JHU). It provides expertise for the design of quantitative magnetic resonance imaging (MRI) and spectroscopy (MRS) data acquisition and processing technologies that facilitate the biomedical research of a large community of clinicians and neuroscientists in Maryland and throughout the USA. These methods allow noninvasive assessment of changes in brain anatomy as well as in tissue metabolite levels, physiology, and brain functioning while the brain is changing size during early development and during neurodegeneration, i.e. the changing brain throughout our life span. The Kirby Center has 3 Tesla and 7 Tesla state of the art scanners equipped with parallel imaging (8, 16, and 32-channel receive coils) and multi-transmit capabilities. CIS has an IBM supercomputer that is part of a national supercomputing infrastructure.