Explore more about: Digestive Diseases

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A Vanderbilt Institute for Surgery and Engineering research team is conducting the first phase 1 clinical trial of a magnetic, flexible endoscope that has the potential to provide a safer alternative to standard colonoscopy, particularly for individuals with inflammatory bowel disease. Source: Nashville Medical News
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Research into what is known as the gut-brain axis continues to reveal how the brain and gut influence each other’s health and well-being. Now researchers are endeavoring to learn more about gut-brain discourse using a model system built in a lab dish.
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A team of experts from engineering, neuroscience, applied microbiology, and physics has been making headway on building a platform that can monitor and model the real-time processing of gut microbiome serotonin activity.
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Biological engineers have created a multitissue model that lets them study the relationships between different organs and the immune system on a microfluidic chip seeded with human cells. With this 'organs-on-a-chip' model, they could explore the role of immune cells in ulcerative colitis and other inflammatory diseases.
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Most medicines work by binding to and blocking the effect of disease-causing molecules. Now, to accelerate the identification of potential new medicines, bioengineers have created a computer model that mimics the way molecules bind.
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Engineers have developed a light-sensitive material that allows gastrointestinal devices to be triggered to break down inside the body when they are exposed to light from an ingestible LED.
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A wearable monitoring device to make treatments easier and more affordable for the millions of people with swallowing disorders is about to be released into the market.
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MIT engineers designed a drug capsule that can carry insulin or other protein drugs and protect them from the harsh environment of the gastrointestinal tract. When the capsule reaches the small intestine, it breaks down to reveal dissolvable microneedles that attach to the intestinal wall and release drug for uptake into the bloodstream.