Explore more about: Stem Cells

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Sickle cell disease leads to chronic pain, organ failure, and early death in patients worldwide. A team has demonstrated a gene editing approach that efficiently corrects the mutation underlying SCD in patient blood stem cells and in mice. This treatment rescued disease symptoms in animal models, enabling long-lasting production of healthy blood cells, and could inspire a therapeutic strategy for SCD.
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In a groundbreaking new study, researchers have 3D printed a functioning centimeter-scale human heart pump in the lab. The discovery could have major implications for studying heart disease, the leading cause of death in the United States killing more than 600,000 people a year.
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Bioengineers have created a 3D-printed scaffold designed to regenerate complex tissues composed of multiple layers of cells with different biological and mechanical properties.
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Bioengineers used bone engineered in a 3D-printed mold and grown alongside the ribs of sheep to successfully replace a portion of the animals’ jaw bones.
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NIBIB-funded researchers have developed a 3D-printed scaffold coated in aggrecan, a native cartilage component, to improve the regeneration of cartilage tissue in joints.
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A process using human stem cells can generate the cells that cover the external surface of a human heart.
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A new technique discovered for generating rapidly-differentiating human neural stem cells for use in a variety of tissue engineering applications.
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A new biomaterial can be used to study how and when stem cells sense the mechanics of their surrounding environment.
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Dr. Gordana Vunjak-Novakovic and her colleagues have managed to create living bone from stem cells. First, they made a CT scan to create a 3-D image of each pig’s jaw. From cow bone, they sculpted a “scaffold” — a three-dimensional copy of the pig bone.
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For the first time, researchers have grown living bone grown to precisely replicate the original anatomical structure, using autologous stem cells.