Explore more about: Cancer

Scientists report they have created a tiny, nanosize container that can slip inside cells and deliver protein-based medicines and gene therapies of any size -- even hefty ones attached to the gene-editing tool called CRISPR.

A novel method produces a new class of radioactive tracers that are used for medical imaging. The method allows them to attach radioactive atoms to compounds that have previously been difficult or even impossible to label.  The advance will make it easier to track medications in the body and identify tumors and other diseases.

The researchers genetically engineered CAR T cells with molecular tags, which they were able to monitor in an animal model using position emission tomography (PET) imaging.

The novel approach better mimics the tumor environment in patients. Made with extracellular matrix (ECM) from pig brains and seeded with tumors from patients, the system is revealing tumor/ECM interactions that aid tumor growth, providing potential targets for new therapies.

Researchers have designed a more precise and versatile genome editing system, named prime editing, that harnesses the power of CRISPR-Cas9 in combination with another protein, reverse transcriptase, to directly edit DNA in human cells.

Learn about Dr. Quyen Nguyen's scientific accomplishments throughout her career journey and her advice for women scientists.

Learn about Dr. Carla Pugh's scientific accomplishments throughout her career journey and her advice for women scientists.

Biography of Gordana Vunjak-Novakovic, Ph.D., a professor of biomedical engineering at Columbia University engineers and builds tissues to improve health and cure disease.

Researchers have developed 3-dimensional human tissue culture models of pediatric and adult brain cancers in a brain-mimicking microenvironment, that includes brain-derived extracellular matrix (ECM) -- the complex network of proteins and amino acids with bound sugars that not only provides support for surrounding neural tissue, but also helps to guide cell growth and development. The development represents a significant advancement for the study of brain tumor biology and pharmacological response.

Women undergoing treatment for ovarian cancer are checked for tumor cells that may have spread to surrounding tissues, but current technologies miss very small metastatic areas. Now a laser microscopy technique is able to identify these regions with great accuracy.