Creating Biomedical Technologies to Improve Health

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Grantee News • December 14, 2017

Scientists have adapted DNA-PAINT technology to microscopes that are widespread among cell biology laboratories, called confocal microscopes, and that are used by researchers to image whole cells and thicker tissues at lower resolution. They have demonstrated that the method can visualize a variety of different molecules, including combinations of different proteins, RNAs and DNA throughout the entire depth of whole cells at super-resolution. Read more at the Harvard Wyss Institute.

Grantee News • December 14, 2017

Much as a frame provides structural support for a house and the chassis provides strength and shape for a car, a team of engineers believes they have a way to create the structural framework for growing living tissue using an off-the-shelf 3-D printer. Read more at Penn State News.

Grantee News • December 8, 2017

Engineers and nutritionists have created a swift solution for a challenging global health problem: a low-cost, rapid test to detect iron and vitamin A deficiencies at the point of care. Read more from Cornell University.

Grantee News • December 8, 2017

Engineers have developed a smartphone case and app that could make it easier for patients to record and track their blood glucose readings, whether they're at home or on the go. Read more at the UC San Diego News Center.

Science Highlights • December 6, 2017
Surgical planning is critical for obtaining the best outcomes, avoiding medical errors, and limiting damage to surrounding nerves and healthy tissues. Now NIBIB-funded scientists have developed a new technique for 3D-printing patient-specific organ models – here the prostate gland -- using polymers that accurately model the prostate’s dimensions and physical properties, while also providing quantitative tactile feedback, or response to pressure, incisions, and suturing.
Science Highlights • December 4, 2017
Eleven years ago, Andrew Meas sustained a spinal cord injury as the result of a collision with an oncoming vehicle while riding his motorcycle. The injury left him paralyzed from the chest down. He enrolled in a study at the University of Louisville in which researchers would investigate whether spinal stimulation, in conjunction with daily training on a treadmill, could restore some ability to move. Meas was able to voluntarily move his legs, reach a standing position with minimal assistance, and stand without assistance during 10-second intervals on each leg and both legs at once.
Grantee News • November 30, 2017

A stem cell-derived in vitro model displays key small intestine characteristics including innate immune responses, according to a new study. Read more at Science Newsline.

Grantee News • November 30, 2017

A newly developed microscope is providing scientists with a greatly enhanced tool to study how neurological disorders such as epilepsy and Alzheimer's disease affect neuron communication. Read more from the Optical Society.

Grantee News • November 30, 2017

A novel technology enables the modeling of human liver transplantation in an experimental setting. Read more at Phys.Org.

Grantee News • November 30, 2017

A new method for delivering chemotherapy nanodrugs has been created that increases the drugs' bioavailability and reduces side-effects. Their study shows that administering an FDA-approved nutrition source prior to chemotherapy can reduce the amount of the toxic drugs that settle in the spleen, liver and kidneys. Read more from Carnegie Melon University.

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