Creating Biomedical Technologies to Improve Health

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Science Highlights • June 27, 2008
A new device, the size of a cell phone, may hold the key to better monitoring of sleep. Developed by researchers at Beth Israel Deaconess Medical Center in Boston, the device provides a three-dimensional map of sleep quality at a fraction of the time and cost required in a traditional sleep lab.
Grantee News • June 18, 2008
Customized microscopic magnets that might one day be injected into the body could add color to magnetic resonance imaging (MRI), while also potentially enhancing sensitivity and the amount of information provided by images, researchers at the National Institute of Standards and Technology (NIST) and National Institutes of Health (NIH) report.
Science Highlights • May 28, 2008
To fully realize the promise of personalized medicine, researchers and clinicians need tools to track the body’s response to both disease progression and therapy. A novel PET/MRI imaging system developed by a University of California, Davis-led team may be poised to overtake PET/CT as the workhorse of cancer, cardiovascular, and brain imaging studies.
Science Highlights • April 29, 2008
Researchers at the University of California, Davis have developed a dedicated breast CT scanner that provides three-dimensional images of the breast that are comparable to mammograms and does so without the discomfort sometimes associated with the conventional technique.
Science Highlights • March 31, 2008
Unchecked, a rare lung disease – idiopathic pulmonary arterial hypertension (IPAH) – leads to heart failure and death. Understanding the mechanism that promotes thickening of the pulmonary artery is a key to arresting the disease’s progress. Using a new nanoscale platform developed by a team at the University of Pennsylvania and Johns Hopkins University, researchers are beginning to examine how cells in IPAH patients differ from normal individuals and how they respond to the application of external forces.
Science Highlights • February 29, 2008
Disease and injuries damage cartilage in joints, resulting in painful and restricted movement. A Johns Hopkins University research team is developing new techniques for cartilage repair that rely on adhesives.
Science Highlights • January 31, 2008
A simple and inexpensive optical technique developed by a team at Vanderbilt University may help researchers arrest the growth of cataracts in aging eyes, as well as provide a powerful tool to diagnose disease. Based on backscatter interferometry, the device provides quick readouts 10,000 times more sensitive than conventional molecular surveillance methods.
Science Highlights • December 28, 2007
Multimodal multiphoton microscopy – a novel imaging technology – provides superb detail and 3D resolution, even when imaging deep into tissues such as spinal cord and blood vessels. Using this state-of-the-art approach, Ji-Xin Cheng and his collaborators at Purdue University are looking for ways to improve diagnostics and treatments for various diseases, including multiple sclerosis and heart disease.
Science Highlights • November 30, 2007
Existing surgical simulation techniques often fall short of realism. A new advance in simulation from researchers at Rensselaer Polytechnic Institute will provide doctors the opportunity to learn new medical procedures and hone motor skills without risking the health and safety of their patients. Soon, surgeons will be able to more realistically practice operations in which bleeding and smoke from cauterization can impact the procedure.
Science Highlights • October 26, 2007
A research team from Northwestern University has developed a new technique to noninvasively track changes related to pancreatic cancer and to do so without disturbing the highly sensitive organ. This work may clear the way for new screening tools to discover the disease at its earliest stages.

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