Creating Biomedical Technologies to Improve Health



Grantee News • May 31, 2017

A mechanism that controls the formation and function of plate-like nanocrystals that play a critical role in bone composition has now been discovered by researchers. Read more at University of Arkansas News.

Science Highlights • May 15, 2017
Researchers funded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) have developed a new tool for detecting early pancreatic cancer. The tool uses light-scattering spectroscopy (LSS), bouncing light off targeted tissue to detect structural changes in tissue. The researchers performed a series of pilot studies using LSS and accurately distinguished benign cysts, cancerous cysts, and those with malignancy potential 95 percent of the time. The Harvard University team reported their results in the March 13, 2017, issue of Nature Biomedical Engineering.
Grantee News • May 11, 2017

Engineering researchers have developed a revolutionary process for 3D printing stretchable electronic sensory devices that could give robots the ability to feel their environment. The discovery is also a major step forward in printing electronics on real human skin. Read more at University of Minnesota News.

Grantee News • May 11, 2017

Biomedical engineers are now able to take a live, holistic look at the inner workings of a small animal with enough resolution to see active organs, flowing blood, circulating melanoma cells and firing neural networks. The technique uses the best of both light and ultrasound, breaking long-standing resolution and speed barriers in small-animal whole-body imaging, providing full cross-sectional view of a small animal's internal functions in real-time. Read more at Duke Pratt School of Engineering News.

Science Highlights • May 10, 2017
A research team funded by the National Institute of Biomedical Imaging and Bioengineering has engineered a small peptide that binds to a protein found in high-risk prostate cancers. By linking the peptide to a clinically used MRI contrast agent, the group used MRI to identify aggressive, metastatic tumors in mouse models of prostate cancer. The system is a promising step for reliable early detection and treatment of high-risk, life-threatening prostate cancer.
Grantee News • May 2, 2017

Studies have suggested a link between fitness and memory, but researchers have struggled to find the mechanism that links them. A new study found that the key may lie in the microstructure of the hippocampus, a region in the middle of the brain involved in memory processes. Read more at Illinois Research News.

May 1, 2017

An ingestible electronic capsule, complete with a capsule-sized antenna capable of receiving a radio signal wirelessly, can safely power a device in the gastrointestinal tract in preclinical models, investigators report. Read more at MIT News.

Grantee News • April 21, 2017

A significant step has been made toward breaking the so-called 'color barrier' of light microscopy for biological systems, allowing for much more comprehensive, system-wide labeling and imaging of a greater number of biomolecules in living cells and tissues than is currently attainable. The advancement has the potential for many future applications, including helping to guide the development of therapies to treat and cure disease. Read more at Science Newsline.

Science Highlights • April 21, 2017
Biomaterials expert Dr. Jennifer West is a leader in her cutting-edge field: a founding inventor at two companies, holder of 20 biotechnology patents, and the Fitzpatrick Family University Professor of Engineering and associate dean for Ph.D. education at Duke University’s Pratt School of Engineering. She visited NIH on March 22 to speak at the NIH Director’s Wednesday Afternoon Lecture Series.
Science Highlights • April 18, 2017
Malaria affects hundreds of millions of people every year, killing more than half a million. Part of the difficulty of eliminating malaria stems from the fact that a large portion of the at-risk population lives in rural areas where access to doctors can be a challenge. This means that many patients often do not comply with the strict daily schedule malaria prevention medicines require. Researchers funded by NIBIB at MIT have developed a capsule that, when dissolved in the stomach, releases a star-shaped material containing drugs that help to prevent malaria infections and lasts for up to two weeks.