Creating Biomedical Technologies to Improve Health

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Science Highlights • February 25, 2014
By injecting mice with tiny, negatively charged particles following infection or damage to tissue, researchers were able to prevent additional harm to tissues, normally caused by excessive inflammation. The particles caused inflammatory monocytes—cells that secrete damaging proteins at the sites of injured or diseased tissue—to be diverted instead to the spleen, where they eventually died.
NIBIB in the News • February 14, 2014

During his recent visit to the NIH, Bill Gates made a welcomed prediction. “We’re just at the beginning of what we can do together,” he asserted, referring to the combined efforts of the NIH and the Bill and Melinda Gates Foundation to improve healthcare for the world’s most impoverished nations. Gates was invited to deliver the NIH’s 2013 David E. Barmes Global Health Lecture in December.

Grantee News • February 4, 2014

SBIR grant recipient, Stephen Aylward, and colleagues recently released a publicly accessible, annotated ultrasound video database, developed in conjunction with their research on automated detection algorithms to help non-expert users identify target structures. This technology could also help first responders assess trauma victims quickly and accurately. Read the full article at kitware.com.

Science Highlights • January 24, 2014
In a common surgery for non-melanoma skin cancer, known as Mohs surgery, the surgeon successively removes the cancer and surrounding tissue, which is processed and checked for residual cancer -- a process that takes 20 - 45 minutes and is often repeated numerous times. Now, NIBIB-funded researchers have developed a microscopic technique to analyze removed tissue rapidly right in the clinic -- dramatically reducing the length, inefficiency, and expense of this procedure.
Grantee News • January 23, 2014

Using high-resolution imaging, NIBIB grantee Robert Singer and colleagues at Albert Einstein College of Medicine of Yeshiva University observed in real-time and in living neurons a possible molecular mechanism related to making memories in a mouse model with fluorescently-tagged mRNA molecules, also developed by Singer et al. Read the full press release and see a video of the glowing mRNA molecules in motion at einstein.yu.edu.

Grantee News • January 21, 2014

A device that can monitor the levels of specific drugs as they flow through the bloodstream may soon take the guesswork out of drug dosing and allow physicians to tailor prescriptions to their patients’ specific biology. Developed by UC Santa Barbara researchers Tom Soh, Kevin Plaxco and Scott Ferguson, the biosensor combines engineering and biochemistry and has far-reaching potential. Read the full press release at news.ucsb.edu. 

Grantee News • January 21, 2014

An international research team led by NIH-funded investigators, including NIBIB grantees Zahi Fayad and David Carmode, have shown that a new statin nanotherapy can target high-risk inflammation inside heart arteries to prevent repeat heart attacks and stroke. Read the full press release at mountsinai.org.

Grantee News • January 17, 2014

Researchers from Northwestern Medicine and the University of Sydney in Australia have found that inflammatory damaged is decreased by half when microparticles are injected into the blood stream within 24 hours of the attack, according to new preclinical research. Read the full press release at Northwestern.edu

Science Highlights • January 16, 2014

Researchers funded by the National Institutes of Health have developed a high-resolution MRI technique to visualize disruptions in energy metabolism in the heart, often a sign of disease. The technique could help doctors identify damaged heart tissue earlier in patients with coronary artery disease or other heart disorders.

NIBIB in the News • January 10, 2014

Science enthusiasts snacked on “instant” ice cream made with liquid nitrogen, tried their hands at virtual surgery, sat in the driver’s seat of a new Tesla Model S electric car and learned about a prototype for the world’s first reusable rocket, all during National Geographic’s recent “Science of Everything” fair in Washington, D.C.

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