Creating Biomedical Technologies to Improve Health

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Science Highlights • January 28, 2013
An NIBIB grantee has developed a dedicated breast CT scanner that allows the breast to be imaged in three dimensions and could help radiologists detect hard-to-find tumors. The scanner uses a radiation dose comparable to standard x-ray mammography and doesn’t require compression of the breast.
Grantee News • January 23, 2013
NIBIB-funded research by multiple teams including Andrea Adamo, Robert Langer, Armon Sharei, Janet Zoldan at the Massachusetts Institute of Technology has yielded a new method to deliver large molecules through a cell membrane using a microfluidic chip. The discovery may lead to new disease treatments, as well as new system for vaccination and is described in the Proceedings of the National Academy of Sciences. Read the full article from Science Daily.
NIBIB in the News • January 14, 2013

In a small study, researchers reported increased healthy tissue growth after surgical repair of damaged cartilage if they put a "hydrogel" scaffolding into the wound to support and nourish the healing process. Read the full article at ScienceDaily.com

Grantee News • January 11, 2013

Research done in collaboration with the NIBIB-funded Center for Biomedical Optical Coherence Tomography Reseach and Translation based at Massachusetts General Hospital, has led to the development of a pill-sized imaging system for the upper gastrointestinal tract. The tethered capsule technique was reported online January 13 in Nature Medicine.

Grantee News • January 9, 2013

Breakthrough research in human cartilage repair by NIBIB grantees Jennifer Elisseeff, Ph.D. at Johns Hopkins University and Garry E. Gold at Stanford University may improve the treatment of cartilage defects. A pilot clinical study demonstrated the efficacy of an adhesive hydrogel biomaterial to support cartilage formation. Magnetic resonance imaging confirmed repair tissue fill, growth, and integration with surrounding cartilage.

Grantee News • December 24, 2012
A new spectroscopy technique developed at an NIBIB-funded research center promises faster and less expensive breast cancer diagnosis. Diffuse reflectance spectroscopy could reduce the rate of inconclusive diagnoses and be used during biopsy procedures, providing accurate results within seconds. Read the full article from Proceedings of the National Academy of Sciences.
Grantee News • December 21, 2012
NIBIB Training Program grantee Joseph DeRisi highlights the importance of cross disciplinary training programs, with special focus on the Physiology Course at the Marine Biological Laboratory (MBL), to explore areas outside their respective areas of expertise, gain exposure to other disciplines, and better understand a problem’s significance. Read the full article from Science.
Grantee News • December 12, 2012

NIBIB-funded researcher Stan Opella, Ph.D, has developed a new technique for determining the structure of G-Protein coupled receptors (GPCRs,) one which does not require the massive physiological modifications demanded from the current technology, X-ray crystallography. Read a related article from the NIBIB: Understanding Critical Protein Structures May Speed Drug Development.

Science Highlights • December 10, 2012

Researchers at Duke University have developed a new ultrasound imaging technique that non-invasively detects tumors and fibrosis in the liver, thus avoiding the pain and complications associated with biopsy. These researchers are also extending the technique to aid in diagnosing other diseases, as well.

NIBIB in the News • December 10, 2012
The mHealth summit last week in Washington, D.C. provided conference attendees with the opportunity to evaluate the state of the field, discuss regulatory issues, and ponder the future of mobile health technologies. Read the full article from The Atlantic.

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