Creating Biomedical Technologies to Improve Health



Science Highlights • December 1, 2016
Gene therapies could revolutionize medicine, including many forms of cancer treatment. For their potential to be realized, however, biomedical researchers must develop ways to prevent unintended immune responses and cell mutations. To achieve the benefits of gene therapy without negative side effects, NIBIB grantee Jordan J. Green, Ph.D., develops biodegradable nanoparticles that can be biochemically engineered to carry therapies that can seek out and kill cancer tumors.
Grantee News • November 29, 2016

In the near future, hemophiliacs could be able to treat their disease by simply swallowing a capsule. Thanks to a new breakthrough, treatment for hemophilia can now be administered via a biodegradable system, a capsule, giving people affected by the hereditary bleeding disorder hope for a less expensive, less painful treatment option than conventional injections or infusions. Read more at UT News.

Science Highlights • November 29, 2016
By significantly increasing the speed of functional MRI (fMRI), NIBIB-funded researchers have been able to image rapidly fluctuating brain activity during human thought. fMRI measures changes in blood oxygenation, which were previously thought to be too slow to detect the subtle neuronal activity associated with higher order brain functions. The new discovery is a significant step towards realizing a central goal of neuroscience research: mapping the brain networks responsible for human cognitive functions such as perception, attention, and awareness.
Grantee News • November 25, 2016

A research team has developed a first-of-its-kind soft, flexible microfluidic device that easily adheres to the skin and measures the wearer's sweat to show how his or her body is responding to exercise. Read more at Northwestern Research News.

Grantee News • November 22, 2016

Scientists report using human pluripotent stem cells to grow human intestinal tissues that have functioning nerves in a laboratory, and then using these to recreate and study a severe intestinal nerve disorder called Hirschsprung’s disease. Read more at Engadget.

Grantee News • November 17, 2016

Imagine swallowing a pill today that continues releasing the daily dose of a medicine you need for the next week, month or even longer. Investigators have developed a long-acting drug delivery capsule that may help to do just that in the future. To test the capsule's real-world applications, the team used both mathematical modeling and animal models to investigate the effects of delivering a sustained therapeutic dose of a drug called ivermectin, which is used to treat parasitic infections. Read more at MIT News.

Grantee News • November 17, 2016

A new biomaterial is under development that has potential to protect patients at high risk for bleeding in surgery, report researchers. Read more at BioPortfolio.

Science Highlights • November 15, 2016
Data scientists have discovered seven genetic variants linked to intracranial volume, Parkinson’s disease risk, and cognitive ability.
Grantee News • November 10, 2016

Researchers have combined one of nature’s tiny miracles, the diatom, with a version of inkjet printing and optical sensing to create an exceptional sensing device that may be up to 10 million times more sensitive than some other commonly used approaches. Read more at Phys.Org.

Grantee News • November 7, 2016

A new imaging technique stimulates particles to emit laser light and could create higher-resolution images of living tissues, say scientists. Read more at MIT News.