Creating Biomedical Technologies to Improve Health



Science Highlights • March 3, 2014

Kaposi sarcoma is especially prevalent in countries suffering from AIDS—countries which largely have very little infrastructure and where citizens have limited access to health care. NIBIB funded researchers at Cornell University, David Erickson, Ph.D, and his collaborator, Ethel Cesarman are developing a new point of care device that can diagnose this type of cancer in less than 30 minutes and uses very little power.

Grantee News • March 2, 2014

NIBIB grantee Wei Min coupled physics and chemistry to devise a novel imaging technique for imaging small biomolecules, such as small molecular drugs, nucleic acids, amino acids, or lipids, in live cells and animals. Read the full press release at

Science Highlights • February 27, 2014

NIBIB has established a collaboration with research teams in the U.S., Ireland, and Northern Ireland to tackle a particularly difficult and significant global health problem: the lack of an accurate and reliable test for prostate cancer and the need to provide more precise grading and staging of the cancer to guide optimal treatment. The device under development will use microfluidic nanowell arrays that can rapidly detect multiple cancer biomarkers in a single drop of blood.

Grantee News • February 26, 2014

Compared to a traditional flu shot, most people said they'd prefer self-vaccinating with an easy-to-use microneedle patch currently being developed by NIBIB grantee Mark Prausnitz, of Georgia Tech, and colleagues at Emory University and the CDC. This technology may help boost immunization rates, reduce flu-related deaths and hospitalizations, and lower costs for storing and administering vaccines. Read the full press release at

Science Highlights • February 25, 2014
By injecting mice with tiny, negatively charged particles following infection or damage to tissue, researchers were able to prevent additional harm to tissues, normally caused by excessive inflammation. The particles caused inflammatory monocytes—cells that secrete damaging proteins at the sites of injured or diseased tissue—to be diverted instead to the spleen, where they eventually died.
NIBIB in the News • February 14, 2014

During his recent visit to the NIH, Bill Gates made a welcomed prediction. “We’re just at the beginning of what we can do together,” he asserted, referring to the combined efforts of the NIH and the Bill and Melinda Gates Foundation to improve healthcare for the world’s most impoverished nations. Gates was invited to deliver the NIH’s 2013 David E. Barmes Global Health Lecture in December.

Grantee News • February 4, 2014

SBIR grant recipient, Stephen Aylward, and colleagues recently released a publicly accessible, annotated ultrasound video database, developed in conjunction with their research on automated detection algorithms to help non-expert users identify target structures. This technology could also help first responders assess trauma victims quickly and accurately. Read the full article at

Science Highlights • January 24, 2014
In a common surgery for non-melanoma skin cancer, known as Mohs surgery, the surgeon successively removes the cancer and surrounding tissue, which is processed and checked for residual cancer -- a process that takes 20 - 45 minutes and is often repeated numerous times. Now, NIBIB-funded researchers have developed a microscopic technique to analyze removed tissue rapidly right in the clinic -- dramatically reducing the length, inefficiency, and expense of this procedure.
Grantee News • January 23, 2014

Using high-resolution imaging, NIBIB grantee Robert Singer and colleagues at Albert Einstein College of Medicine of Yeshiva University observed in real-time and in living neurons a possible molecular mechanism related to making memories in a mouse model with fluorescently-tagged mRNA molecules, also developed by Singer et al. Read the full press release and see a video of the glowing mRNA molecules in motion at

Grantee News • January 21, 2014

A device that can monitor the levels of specific drugs as they flow through the bloodstream may soon take the guesswork out of drug dosing and allow physicians to tailor prescriptions to their patients’ specific biology. Developed by UC Santa Barbara researchers Tom Soh, Kevin Plaxco and Scott Ferguson, the biosensor combines engineering and biochemistry and has far-reaching potential. Read the full press release at