Creating Biomedical Technologies to Improve Health

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Science Highlights • December 7, 2018
NIBIB-funded researchers have created a novel, low-cost biosensor to detect HER-2, a breast cancer biomarker in the blood, allowing for a far less invasive diagnostic test than the current practice, a needle biopsy. Scientists at the Universities of Hartford and Connecticut and funded in part by NIBIB, combined microfluidic technology with diagnostics, including electrochemical sensors and biomarkers, into a powerful package that can give results in about 15 minutes.
Science Highlights • December 6, 2018
Tuberculosis meningitis causes life-threatening inflammation of the membranes in the brain and spinal cord. Treatment is difficult due to the inability of drugs to penetrate the blood brain barrier (BBB). Now researchers are using non-invasive PET imaging to measure antibiotic concentrations in infected brain tissue with the goal of optimizing TB meningitis treatment.
Grantee News • December 6, 2018
A new test for chlamydia can provide results within 30 minutes, potentially speeding up the start of treatment, researchers say. Read more from WebMD
Grantee News • December 3, 2018

A new, low-cost wound dressing could dramatically speed up healing in a surprising way. The method leverages energy generated from a patient's own body motions to apply gentle electrical pulses at the site of an injury. Read more form University of Wisconsin-Madison News.

Science Highlights • November 30, 2018
A team of NIH-funded researchers at the University of Arkansas have demonstrated the novel use of multiphoton microscopy to monitor wound healing in live animals. The scientists measured metabolic changes that occur during healing at the wounds’ surface using autofluorescence imaging. In the future, doctors could use the images to non-invasively diagnose the type of chronic wound and determine the best treatment strategy.
Science Highlights • November 28, 2018
NIBIB-funded researchers recently validated a rapid STD test that delivered accurate results in about 30 minutes for chlamydia, allowing patients to receive treatment immediately, thereby stemming the further spread of disease. Other analyses showed most women preferred the easy self-collection method the test offers.
Grantee News • November 27, 2018

A material based on a natural product of bones and citrus fruit, called citrate, provides the extra energy that stem cells need to form new bone tissue, according to bioengineers. Their new understanding of the mechanism that allows citrate to aid in bone regeneration will help the researchers develop slow-release, biodegradable, citrate-releasing scaffolds to act as bone-growth templates to speed up healing in the body. Read more from Penn Sate News.

NIBIB in the News • November 6, 2018

Microfluidics—the manipulation of fluids on a microscopic scale— has made it possible to produce “lab-on-a-chip” devices that detect, for example, infectious agents like viruses in a single drop of blood. Now, NIBIB researchers have developed microfluidic fibers that can be stretched hundreds of feet--vastly improving the speed and precision of microfluidic analysis of biological fluids. Read more on the NIH Director's Blog.

Grantee News • November 5, 2018

Miniscule nanostraws could help solve the problem of how to deliver precise doses of molecules directly into many cells at once. Read more from Stanford News.

Science Highlights • October 31, 2018
NIBIB funded researchers have developed laser-activated nanomaterials that integrate with wounded tissues to form seals that are superior to sutures for containing body fluids and preventing bacterial infection.

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