Creating Biomedical Technologies to Improve Health



Grantee News • January 9, 2013

Breakthrough research in human cartilage repair by NIBIB grantees Jennifer Elisseeff, Ph.D. at Johns Hopkins University and Garry E. Gold at Stanford University may improve the treatment of cartilage defects. A pilot clinical study demonstrated the efficacy of an adhesive hydrogel biomaterial to support cartilage formation. Magnetic resonance imaging confirmed repair tissue fill, growth, and integration with surrounding cartilage.

Grantee News • December 24, 2012
A new spectroscopy technique developed at an NIBIB-funded research center promises faster and less expensive breast cancer diagnosis. Diffuse reflectance spectroscopy could reduce the rate of inconclusive diagnoses and be used during biopsy procedures, providing accurate results within seconds. Read the full article from Proceedings of the National Academy of Sciences.
Grantee News • December 21, 2012
NIBIB Training Program grantee Joseph DeRisi highlights the importance of cross disciplinary training programs, with special focus on the Physiology Course at the Marine Biological Laboratory (MBL), to explore areas outside their respective areas of expertise, gain exposure to other disciplines, and better understand a problem’s significance. Read the full article from Science.
Grantee News • December 12, 2012

NIBIB-funded researcher Stan Opella, Ph.D, has developed a new technique for determining the structure of G-Protein coupled receptors (GPCRs,) one which does not require the massive physiological modifications demanded from the current technology, X-ray crystallography. Read a related article from the NIBIB: Understanding Critical Protein Structures May Speed Drug Development.

Science Highlights • December 10, 2012

Researchers at Duke University have developed a new ultrasound imaging technique that non-invasively detects tumors and fibrosis in the liver, thus avoiding the pain and complications associated with biopsy. These researchers are also extending the technique to aid in diagnosing other diseases, as well.

NIBIB in the News • December 10, 2012
The mHealth summit last week in Washington, D.C. provided conference attendees with the opportunity to evaluate the state of the field, discuss regulatory issues, and ponder the future of mobile health technologies. Read the full article from The Atlantic.
NIBIB in the News • December 9, 2012
At the recent mHealth summit in Washington, D.C., Dr. Pettigrew described the handheld Diagnostic Magnetic Resonance (DMR) device developed by NIBIB-funded researchers at Massachusetts General Hospital. Read the full article from Vanguard.
Grantee News • November 24, 2012

The New York Times features NIBIB grantees Bob Langer and Ralph Weissleder as being “on the front lines of turning discoveries made in the lab into a range of drugs and drug deliver systems. Without this kind of technology transfer, the thinking goes, scientific discoveries might well sit on the shelf, stifling innovation.” Read the full article from The New York Times.

Grantee News • November 20, 2012

NIBIB-funded research has resulted in a new spectrum of voltage-sensitive dyes (VSDs) that improves optical imaging of brain and heart electrical activity. Fluorinated hemicyanine dyes provide spectral compatibility with newly available optical technologies, offering better photostability and improving the signal to noise ratio (S:N) of the optically recorded voltage activity in cells, tissues, and organs. Read the full article from Proceedings of the National Academy of Sciences.

NIBIB in the News • November 19, 2012
NIBIB-funded researchers at Northwestern develop new approach to treat autoimmune disease. Comments by William Heetderks, Ph. D., NIBIB Associate Director of Extramural Programs are included. Read more about breakthroughs regarding the immune system and Multiple Sclerosis.