Creating Biomedical Technologies to Improve Health

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Science Highlights • September 30, 2009
Preserving fertility is a major concern for women and girls facing cancer diagnosis because chemotherapy and radiation are harmful to the ovaries. Scientists are developing 3-D scaffolds that mimic the ovary so that immature egg cells could be matured outside of the body. The technology will allow women to freeze their ovarian tissue for use at a later time, without the need for time-consuming ovarian stimulation.
Science Highlights • August 31, 2009
Different diseases affect the shape of blood vessels. Cancer, for instance, tends to change vessels from smooth tubes into jagged conduits. But conventional imaging alone cannot reveal key details about a blood vessel’s shape. By combining magnetic resonance angiography with computer analysis, researchers at the University of North Carolina, Chapel Hill, have developed a noninvasive method to assess tumor malignancy and to track response to drug therapy. The approach also offers insight into how the brain ages.
Press Releases • August 17, 2009
The National Institute of Biomedical Imaging and Bioengineering (NIBIB), part of the National Institutes of Health, announced today that it has awarded ten Phase II interdisciplinary research training grants totaling $16 million over five years.
Science Highlights • July 22, 2009
Communication is a challenge for people who are locked into their bodies as a result of a severe neuromuscular condition such as Lou Gehrig’s disease (ALS) or brainstem stroke. By training the brain to control its own electrical activity rather than the body’s muscles, researchers at the Wadsworth Center, New York State Department of Health, Albany, are helping these individuals remain connected to their families, friends, and colleagues and are opening up new possibilities for brain-computer interactions.
Press Releases • July 1, 2009
A new imaging technique, once validated in mice and pending further experiments, could provide a real-time noninvasive method for identifying tumors in humans who express HER2 and who would be candidates for targeted therapy directed against this protein.
Grantee News • June 30, 2009
A research team headed by Drs. Mehmet Toner, Ph.D. and Daniel Haber, M.D., Ph.D., of the Massachusetts General Hospital Cancer Center, has been awarded a $15 million research grant from the proceeds raised by the Entertainment Industry Foundation during their landmark Stand Up to Cancer (SU2C) telethon.
Science Highlights • June 29, 2009
For too long the blood-brain barrier has kept potentially life-saving drugs from entering the central nervous system and brain. Now researchers from Harvard Medical School and the Sunnybrook Health Science Center, University of Toronto, have developed an ultrasound technique that temporarily opens the blood-brain barrier allowing drug therapies for diseases from cancer to Alzheimer’s to pass into the central nervous system.
Science Highlights • May 31, 2009
Advances in technology have contributed to the growth of electronic medical data systems, increasing concern among patients and health care providers about the confidentiality of clinical information. NIBIB-funded investigators have created software to aggregate and share health data with researchers while maintaining patient confidentiality.
Science Highlights • April 30, 2009
A new microscope the size of a bumblee’s hair bristle could change disease diagnosis in remote areas of the world as well as home-based disease monitoring. Developed by researchers at the California Institute of Technology, Pasadena, the lensless microscope relies on tubes and channels to guide samples through a chamber. A sensor similar to those used in digital cameras records the images.
Science Highlights • March 31, 2009
Embryonic stem (ES) cells have shown great promise in the creation of replacement cells and tissues to treat a number of diseases. Scientists at Baylor College identified a new protein, Ronin, which has potential for preserving stem cells for use in many medical applications.

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