Creating Biomedical Technologies to Improve Health

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Grantee News • November 20, 2012

NIBIB-funded research has resulted in a new spectrum of voltage-sensitive dyes (VSDs) that improves optical imaging of brain and heart electrical activity. Fluorinated hemicyanine dyes provide spectral compatibility with newly available optical technologies, offering better photostability and improving the signal to noise ratio (S:N) of the optically recorded voltage activity in cells, tissues, and organs. Read the full article from Proceedings of the National Academy of Sciences.

Press Releases • November 19, 2012
In a mouse model of multiple sclerosis (MS), researchers funded by the National Institutes of Health have developed innovative technology to selectively inhibit the part of the immune system responsible for attacking myelin–the insulating material that encases nerve fibers and facilitates electrical communication between brain cells.
Grantee News • November 19, 2012

In a mouse model of multiple sclerosis (MS), NIBIB-funded researchers Stephen Miller and Lonnie Shea at Northwestern University have developed innovative biotechnology to selectively inhibit the part of the immune system responsible for attacking myelin–the insulating material that encases nerve fibers and facilitates electrical communication between brain cells. Read the full article from Northwestern University.

Science Highlights • November 19, 2012
A picture speaks a thousand words, and when the picture is an x-ray, ultrasound, MRI scan, or other medical image, it is an essential chapter in a person’s health history. Every day, doctors, nurses, and other health care professionals rely on such images and other medical multimedia in diagnosing or monitoring illnesses and planning a patient’s care.
NIBIB in the News • November 19, 2012
NIBIB-funded researchers at Northwestern develop new approach to treat autoimmune disease. Comments by William Heetderks, Ph. D., NIBIB Associate Director of Extramural Programs are included. Read more about breakthroughs regarding the immune system and Multiple Sclerosis.
Science Highlights • November 13, 2012

Identifying new compounds to treat heart disease, cancer, or other inflammatory and immune-related disorders may get easier using a precisely tailored application of solid state nuclear magnetic resonance (NMR) spectroscopy–which can reveal a protein’s entire 3-D structure within its natural surroundings.

Grantee News • November 8, 2012
NIBIB grantees Dr. Gordana Vunjak-Novakovic and Dr. Norbert Pelc have been inducted into the National Academy of Engineering (NAE). Founded in 1964, the NAE marshals the expertise and insights of eminent engineers to advise the nation on matters involving engineering and technology.
Grantee News • October 30, 2012

A team of researchers including NIBIB investigator Kit Lam at the University of California Davis has discovered a new class of nanoparticles capable of packaging a diverse array of drugs. Research findings demonstrate structural and dynamic changes within nanoparticles during interaction with blood proteins which will result in better designed nanomedicines that will be therapeutically more efficacious. Read the full article from ACSNano.

Press Releases • October 15, 2012
The National Institutes of Health plans to invest more than $90 million over five years, contingent upon the availability of funds, to accelerate the development and application of single cell analysis across a variety of fields. The goal is to understand what makes individual cells unique and to pave the way for medical treatments that are based on disease mechanisms at the cellular level.
Grantee News • October 12, 2012

Led by a grant from the National Science Foundation (NSF), Mark Chance, PhD, director of the Center for Proteomics and Bioinformatics at Case Western Reserve University School of Medicine, has been awarded $4 million for work with the National Synchrotron Light Source II (NSLS II) at Brookhaven National Laboratory in New York. Read the full news release from Medicus.

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