Creating Biomedical Technologies to Improve Health

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Press Releases • July 27, 2017
Researchers funded by NIH have developed an imaging method that reveals a much more diverse and flexible DNA-protein chromatin chain than previously thought. The result suggests a nimbler structure to regulate gene expression, and provide a mechanism for chemical modifications of DNA to be maintained as cells divide.
Press Releases • July 27, 2017
NIH-funded scientists at the University of Florida have discovered a new method of observing the brain changes caused by Parkinson’s disease, which destroys neurons important for movement. The development suggests that fluid changes in a specific brain area could provide a way to track that damage.
Science Highlights • July 27, 2017
A team of bioengineers supported through a Small Business Innovation Research grant from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) has developed a pocket-sized, ultrasound imaging device to aid doctors in accurately placing needles into the lumbar, or lower, spine.
Science Highlights • July 25, 2017
NIBIB-funded researchers have developed a revolutionary 3-D printer that paves the way for direct printing of biomedical devices onto human skin. The printer builds flexible electronic sensors that measure pressure.  They’re expected to improve sensation in prosthetic hands and surgical robotic arms.
Science Highlights • July 20, 2017
“Seeing is believing,” has been taken to heart by researchers as they strive to develop microscopes that will reveal biological structures and processes with increased clarity and detail. Now, researchers funded by the National Institute of Biomedical Imaging and Bioengineering have developed a technique that uses the vibration of chemical bonds to produce specific colors that allow them to simultaneously observe, in cells and tissues, as many as 24 interacting molecules--each with a distinct color.
Grantee News • July 14, 2017

A metal-free MRI contrast agent has been developed that could be safer for certain patients. The compound contains organic molecules called nitroxides instead of metal and may be used to generate more informative MRI scans of tumors. Read more at MIT News.

Press Releases • July 7, 2017
Using a larger dataset than for any previous human movement study, National Institutes of Health-funded researchers at Stanford University in Palo Alto, California, have tracked physical activity by population for more than 100 countries. Their research follows on a recent estimate that more than 5 million people die each year from causes associated with inactivity.
Grantee News • July 5, 2017

A new portable device can quickly find markers of deadly, unpredictable sepsis infection from a single drop of blood. The device is the first to provide rapid, point-of-care measurement of the immune system's response, without any need to process the blood. This can help doctors identify sepsis at its onset, monitor infected patients and could even point to a prognosis. Read more at Illinois News Bureau.

Science Highlights • June 29, 2017
A new microscope merges different microscopy methods to increase resolution and contrast in thick biological samples. A key component of the method is two-photon microscopy, used to generate a small point of light deep inside the sample. By moving this light throughout the sample and collecting information on how it is being distorted, Shroff and his team are able to adjust the shape of the mirror to cancel out the distortions, thus creating a clear image of the whole sample.
Science Highlights • June 28, 2017
Preterm birth is the leading cause of neonatal morbidity and mortality. Among the many underlying causes of pregnancy-associated complications, it is known that infection and inflammation are highly significant risk factors. Now, NIBIB-funded researchers have developed a system to capture and identify a scarce blood peptide (a fragment of an inflammatory protein) called P1 that can predict increased risk of preterm birth. Early detection offers the opportunity to begin medical interventions to delay birth or increase fetus viability to save lives and reduce lifelong disabilities.

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