Creating Biomedical Technologies to Improve Health

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NIBIB in the News • December 19, 2013

An NIBIB-funded biomedical engineer at Vanderbilt University has constructed a sponge-like, biodegradable tissue “scaffold” that releases an enzyme-blocking molecule to indirectly activate endogenous pathways and enhance tissue regeneration and wound healing. Read the full release at news.vanderbilt.edu.

Science Highlights • December 13, 2013
Clinicians routinely monitor electrical signals from the brains of traumatic brain injury (TBI) patients to assess the response to treatments such as anti-seizure drugs. However, determining the specific location of injuries, where abnormal electrical activity is generated, has remained elusive. Researchers combined several imaging technologies to track abnormal electrical signals to the specific injury site. Known as inverse localization, the technique promises to enhance patient-specific monitoring and treatment, optimize surgical effectiveness, and improve clinical outcomes for those suffering from traumatic brain injury.
Grantee News • December 12, 2013

Dr. Robert Langer of MIT, currently funded by NIBIB and several other NIH Institutes, was one of six recipients of a 2014 Breakthrough Prize in Life Science from the Breakthrough Prizes in Life Sciences Foundation, a relatively new philanthropic organization that awards $3 million prizes to outstanding scientists in support of forward-thinking research and the pursuit of bold projects. Read the full press release at breakthroughprizeinlifesciences.org.

NIBIB in the News • December 9, 2013

NIBIB program director Antonio Sastre discusses the work of grantee Yuni Dewaraja on refining radiation dosimetry in radioimmunotherapy for non-Hodgkin lymphoma and possible implications for changing the standard of care. Read the full article at healthcare-executive-insight.advanceweb.com.

Grantee News • December 9, 2013

Boston University profiles NIBIB grantee Chris Chen and his work in regenerative medicine. Read the full article at bu.edu.

Grantee News • December 6, 2013

Nanoparticles hold promise for delivering drugs to specific targets in the body, but oral delivery remains out of reach because nanoparticles can't penetrate the lining of the intestinal tract. Researchers at the MIT and Brigham and Women's Hospital have recently developed a way for nanoparticles to break through the intestinal lining of mice, possibly paving the way for their use in oral medications. Read the full story at WSJ.com

Science Highlights • December 2, 2013
An international multidisciplinary team including NIBIB scientists has developed an ultrathin membrane that adheres non-invasively to the skin and can be engineered to carry arrays of diagnostic sensors as well as stimulatory components. The “electronic skin” allows remote monitoring of patients for information such as changes in temperature or circulating levels of drugs or metabolites in the bloodstream. Future applications include drug delivery in response to metabolic changes detected by the diagnostic sensors.
Grantee News • November 27, 2013

Researchers from North Carolina State University and Duke University have developed nanoscale “patches” that can be used to sensitize targeted cell receptors, making them more responsive to signals that control cell activity. The finding holds promise for promoting healing and facilitating tissue engineering research. Read more at North Carolina State.

Grantee News • November 27, 2013

Researchers have long wondered what allows stem cells to persist for decades, when their progeny last for days, weeks or months before they need to be replaced. Now, a study from the University of Pennsylvania has uncovered one of the mechanisms that allow these stem cells to keep dividing in perpetuity. Read more at University of Pennsylvania.

Grantee News • November 27, 2013

A new wireless device has allowed paralyzed people to drive a wheelchair simply by moving their tongues. Read more at livescience.com

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