NEWS & EVENTS
NIBIB-funded research has resulted in a new spectrum of voltage-sensitive dyes (VSDs) that improves optical imaging of brain and heart electrical activity. Fluorinated hemicyanine dyes provide spectral compatibility with newly available optical technologies, offering better photostability and improving the signal to noise ratio (S:N) of the optically recorded voltage activity in cells, tissues, and organs. Read the full article from Proceedings of the National Academy of Sciences.
In a mouse model of multiple sclerosis (MS), NIBIB-funded researchers Stephen Miller and Lonnie Shea at Northwestern University have developed innovative biotechnology to selectively inhibit the part of the immune system responsible for attacking myelin–the insulating material that encases nerve fibers and facilitates electrical communication between brain cells. Read the full article from Northwestern University.
Identifying new compounds to treat heart disease, cancer, or other inflammatory and immune-related disorders may get easier using a precisely tailored application of solid state nuclear magnetic resonance (NMR) spectroscopy–which can reveal a protein’s entire 3-D structure within its natural surroundings.
A team of researchers including NIBIB investigator Kit Lam at the University of California Davis has discovered a new class of nanoparticles capable of packaging a diverse array of drugs. Research findings demonstrate structural and dynamic changes within nanoparticles during interaction with blood proteins which will result in better designed nanomedicines that will be therapeutically more efficacious. Read the full article from ACSNano.
Led by a grant from the National Science Foundation (NSF), Mark Chance, PhD, director of the Center for Proteomics and Bioinformatics at Case Western Reserve University School of Medicine, has been awarded $4 million for work with the National Synchrotron Light Source II (NSLS II) at Brookhaven National Laboratory in New York. Read the full news release from Medicus.