Creating Biomedical Technologies to Improve Health

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Science Highlights • December 22, 2017
NIH researchers have devised a biochemically formulated patch of dissolvable microneedles for the treatment of type 2 diabetes. The biochemical formula of mineralized compounds in the patch responds to blood chemistry to manage glucose automatically. In a proof-of-concept study performed with mice, the researchers showed that the chemicals interact in the bloodstream to regulate blood sugar for days at a time.
Grantee News • December 20, 2017

A study activated genes in human stem cells that initiate biomineralization, a key step in bone formation, according to a science team. Scientists engineered spider web silk combined with silica to activate cell membrane protein receptor integrin. The research will help scientists model intracellular pathways that govern bone formation and efforts to cure diseases such as osteoporosis and calcific aortic valve disease. Read more from the Texas Advanced Computing Center.

Grantee News • December 15, 2017

Scientists have invented a major new advance in DNA nanotechnology. Dubbed 'single-stranded origami,' their new strategy uses one long, thin noodle-like strand of DNA, or its chemical cousin RNA, that can self-fold -- without even a single knot -- into the largest, most complex structures to date. The strands forming these structures can be made inside living cells, opening up the potential for nanomedicine. Read more form Arizona State University.

Grantee News • December 14, 2017

Micro-grippers may be able to navigate unstructured environments and could help reduce risk during surgeries, according to a new study. Read more at Phys.Org.

Grantee News • December 14, 2017

Scientists have adapted DNA-PAINT technology to microscopes that are widespread among cell biology laboratories, called confocal microscopes, and that are used by researchers to image whole cells and thicker tissues at lower resolution. They have demonstrated that the method can visualize a variety of different molecules, including combinations of different proteins, RNAs and DNA throughout the entire depth of whole cells at super-resolution. Read more at the Harvard Wyss Institute.

Grantee News • December 14, 2017

Much as a frame provides structural support for a house and the chassis provides strength and shape for a car, a team of engineers believes they have a way to create the structural framework for growing living tissue using an off-the-shelf 3-D printer. Read more at Penn State News.

Grantee News • December 14, 2017

Cancer imaging can be simplified by a photonic process utilizing molecules derived from horse chestnuts, research shows. Read more at Phys.Org.

Grantee News • December 14, 2017

Using light-emitting nanoparticles, scientists have invented a highly effective method to detect tiny tumors and track their spread, potentially leading to earlier cancer detection and more precise treatment. The technology could improve patient cure rates and survival times. Read more at Medical NewsToday.

Grantee News • December 8, 2017

Engineers and nutritionists have created a swift solution for a challenging global health problem: a low-cost, rapid test to detect iron and vitamin A deficiencies at the point of care. Read more from Cornell University.

Grantee News • December 8, 2017

Engineers have developed a smartphone case and app that could make it easier for patients to record and track their blood glucose readings, whether they're at home or on the go. Read more at the UC San Diego News Center.

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