Creating Biomedical Technologies to Improve Health


May 18, 2015

Nanoparticles Carrying siRNA Inhibit Breast Cancer Metastasis in Mice

NIBIB-funded researchers have designed a nanoparticle-based treatment that inhibits breast cancer metastasis in a mouse model. The nanoparticle carries an siRNA that silences the gene for Beta-3 integrin--a protein that is responsible for the metastasis of breast cancer to other sites in the body. The research team developed the system for difficult-to-treat triple-negative breast cancer and hope to move their experiments from animal models to clinical trials. Read more at ScienceDaily.