Creating Biomedical Technologies to Improve Health

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Grantee News • August 26, 2016

A new biomaterial can be used to study how and when stem cells sense the mechanics of their surrounding environment. With further development, this biomaterial could be used to control when immature stem cells differentiate into more specialized cells for regenerative and tissue-engineering-based therapies. Read more at Penn Medicine News.

Grantee News • August 26, 2016

Ultrasound imaging is used around the world to help visualize developing babies and diagnose diseases. The next step in ultrasound technology is to image not just anatomy, but specific cells and molecules deeper in the body, such as those associated with tumors or bacteria in our gut. Now scientists say that protein engineering techniques might one day lead to colorful ultrasound images of cells deep within our bodies. Read more at Caltech News.

Grantee News • August 26, 2016

A new device using shortwave infrared light could greatly improve ear infection diagnoses and drastically reduce unnecessary antibiotic prescriptions, a major cause of antibiotic resistance. Read more at MIT News.

Grantee News • August 25, 2016

A new study reveals how spontaneous changes in the molecular characteristics of tumors can lead to tumors with a mixed population of cells requiring treatment with several types of therapeutic drugs. Read more at Mass General News.

NIBIB in the News • August 24, 2016

Fierce Biotech reports on a nanovaccine developed by NIBIB researchers that could enhance a current cancer immunotherapy approach while reducing side effects. Read more at fiercebiotech.com.

Science Highlights • August 23, 2016
NIBIB researchers have created a nanovaccine that could make a current approach to cancer immunotherapy more effective while also reducing side effects.
Press Releases • August 23, 2016
In a nation-wide competition, six teams of undergraduate engineering students produced prize-winning designs for technological advances to improve human health. The Design by Biomedical Undergraduate Teams (DEBUT) Challenge winning teams designed tools for a myriad of health care challenges, including diagnosing tuberculosis (TB) in children and a safer alternative for central venous catheter placements.
Grantee News • August 23, 2016

During a heart attack, clots or narrowed arteries block blood flow, harming or killing cells in the heart. But damage doesn't end after the crushing pain subsides. Instead, the heart's walls thin out, the organ becomes enlarged, and scar tissue forms. These changes can cause heart failure. Scientists now report they have developed injectable gels to prevent this damage. Read more and watch the video at ACS News.

Grantee News • August 23, 2016

In a classic experiment, Ivan Pavlov conditioned dogs to salivate at the ringing of a bell. Now, scientists can see what happens in the brains of live animals during this experiment with a new technique. The approach could lead to a greater understanding of how we learn and develop addictions. Read more at ACS News.

Science Highlights • August 23, 2016
Multidrug resistance (MDR) is the mechanism by which many cancers develop resistance to chemotherapy drugs. To address resistance, researchers have developed nanoparticles that simultaneously deliver chemotherapy drugs to tumors and inhibit the MDR proteins that pump the therapeutic drugs out of the cell, rendering tumors highly sensitive to the cancer-killing therapy.

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