Creating Biomedical Technologies to Improve Health

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Grantee News • December 21, 2016

Researchers have invented a transistor-like threshold sensor that can illuminate cancer tissue, helping surgeons more accurately distinguish cancerous from normal tissue. Read more and watch the video at UT Southwestern News.

Science Highlights • December 19, 2016
Researchers funded by the National Institute of Biomedical Imaging and Bioengineering have developed a way to automatically label images of individual vertebrae during spine surgery, preventing mistakes and saving surgeons both time and stress in the operating room. New work recently published by the Johns Hopkins University team demonstrates the accuracy, feasibility, and advantages of having the technology in the operating room.
Grantee News • December 15, 2016

Researchers have been able to generate multifunctional RNA nanoparticles that could overcome treatment resistance in breast cancer, potentially making existing treatments more effective in these patients. Read more at GEN.

Grantee News • December 15, 2016

Researchers have made a major breakthrough that allows people to control a robotic arm using only their minds. The research has the potential to help millions of people who are paralyzed or have neurodegenerative diseases. Read more at University of Minnesota News.

Grantee News • December 9, 2016

Researchers have invented a novel live-cell imaging method that could someday help biologists better understand how stem cells transform into specialized cells and how diseases like cancer spread. The Photonic Crystal Enhanced Microscope (PCEM) is capable of monitoring and quantitatively measuring cell adhesion, a critical process involved cell migration, cell differentiation, cell division, and cell death. Read more at Engineering at Illinois News.

Science Highlights • December 1, 2016
Researchers have created a microfluidic device that can produces millions of droplets containing liver microtissues and could lead to better methods for screening drugs for liver toxicity.
Science Highlights • December 1, 2016
A dime-sized patch of tiny, dissolvable microneedles could be the biomedical advance that expands the reach of vaccines to remote parts of the world, and overcomes fear that prevents many from getting a flu shot each year. Mark Prausnitz, Ph.D., Georgia Institute of Technology, presented the microneedle technology and results from his research leading up to a phase 1 clinical trial during a September 2016 seminar.
Science Highlights • December 1, 2016
Gene therapies could revolutionize medicine, including many forms of cancer treatment. For their potential to be realized, however, biomedical researchers must develop ways to prevent unintended immune responses and cell mutations. To achieve the benefits of gene therapy without negative side effects, NIBIB grantee Jordan J. Green, Ph.D., develops biodegradable nanoparticles that can be biochemically engineered to carry therapies that can seek out and kill cancer tumors.
Grantee News • November 29, 2016

In the near future, hemophiliacs could be able to treat their disease by simply swallowing a capsule. Thanks to a new breakthrough, treatment for hemophilia can now be administered via a biodegradable system, a capsule, giving people affected by the hereditary bleeding disorder hope for a less expensive, less painful treatment option than conventional injections or infusions. Read more at UT News.

Science Highlights • November 29, 2016
By significantly increasing the speed of functional MRI (fMRI), NIBIB-funded researchers have been able to image rapidly fluctuating brain activity during human thought. fMRI measures changes in blood oxygenation, which were previously thought to be too slow to detect the subtle neuronal activity associated with higher order brain functions. The new discovery is a significant step towards realizing a central goal of neuroscience research: mapping the brain networks responsible for human cognitive functions such as perception, attention, and awareness.

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