Explore more about: Synthetic Biological Systems

December 20, 2022
News
NIBIB-funded researchers are developing a new method to treat pancreatic cancer. In their study, they combined an injectable radioactive gel with systemic chemotherapy in multiple mouse models of the disease. The treatment resulted in tumor regression in all evaluated models, an unprecedented result for this genetically diverse and aggressive type of cancer.
October 4, 2022
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NIBIB-funded researchers have developed an interlinked tissue chip system that can model four mature organs in their perspective environments simultaneously. These multi-organ tissue chips could represent a new way to evaluate diseases or drugs that affect multiple different tissues.
April 21, 2022
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Two years ago, Sangeeta Bhatia and Christopher Chen founded a biotech company that on Wednesday officially launched as Satellite Bio in Cambridge, Massachusetts. The company aims to translate the work of Bhatia, Chen and their cofounder Arnav Chhabra into "tissue therapeutics" — regenerative medicines built from bioengineered tissue structures, or "satellites," that can be implanted into patients. Source: BiopharmaDive
March 3, 2022
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In a new study published in Science Translational Medicine, researchers demonstrated that human kidney organoids are useful models to identify the point of permanent and reversible kidney cell damage and they also discovered a drug candidate that could potentially prevent chronic disease before reaching that point. Read more at STAT.
March 2, 2022
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NIBIB-funded researchers are developing a robotic pill that, after swallowing, can deliver biologic drugs into the stomach, which could provide an alternative method for self-injection for a wide range of therapies.
January 5, 2022
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NIBIB-funded researchers have found a way to model the human neuromuscular junction by growing these synapses in a lab, which could accelerate novel treatments for neuromuscular diseases.
October 13, 2021
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With a new $1.3 million grant from the NIBIB, researchers led by University of Florida associate professor Zhoumeng Lin are building a tool that can offer drug researchers insight into how well a new nanoparticle-based cancer therapy will work, even before a drug enters animal testing. Source: Nano Magazine.
September 14, 2021
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Engineers developed a way to grow tiny replicas of the pancreas, using either healthy or cancerous pancreatic cells. Their models could help researchers develop and test potential drugs for pancreatic cancer.
August 31, 2021
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Researchers have developed a capsule that can carry large protein drugs, such as monoclonal antibodies, and inject them directly into the lining of the stomach.
August 30, 2021
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The human body can be genetically inclined to attack its own cells, destroying the beta cells in the pancreas that make insulin, which helps convert sugar into energy. Called Type 1 diabetes, this disorder can occur at any age and can be fatal if not carefully managed with insulin shots or an insulin pump to balance the body's sugar levels.