Biomechanical Engineering

This program supports the design, development, and demonstration of biomechanical technologies for biomedical intervention.


This division supports projects developing and demonstrating new approaches to control/program biology for biomedical intervention, without preference for any particular disease or application. 

Emphasis in this program is on engineering new biomechanical materials, sensors, actuators, and other parts and modules to interface and communicate with human biology and engineered systems for biomedical intervention. These parts and modules act as biotransducers to convert mechanical energy into biological action. Projects should be directed toward overcoming a technological challenge that limits biomedical adoption. This program encourages projects that use a design-build-test approach. 

Examples of biomechanical parts and modules include but are not limited to: 

  • mechano-sensitive scaffolds for modulating tissue
  • microgrippers and drills for surgical robots
  • 3D printed tactile sensors for prosthetics
  • soft elastomeric actuators for assistive devices

Additional Emphasis

Additional emphasis in this program is on the development of screening and processing tools and the discovery of design principles to design, build, and test engineered biomechanical modules. 


The development of integrated systems is supported by the Bionic and Robotic Systems program and Synthetic Biology and Biomimetic Systems program. 

Grant Number Project Title Principal Investigator Institution
1-DP2-EB022358-01 Stretchable, Biodegradable, and Self-Healing Semiconductors for Wearable and Implantable Sensors Darren Lipomi University of California, San Diego
1-DP2-EB024246-01 Origins of human blood lineages in regenerative medicine Sean Bendall Stanford University
5-R01-EB021857-04 Rapid 3D bioprinting of biomimetic vascularized tissue constructs Shaochen Chen University of California, San Diego
5-R01-EB023880-03 Multicomponent solutions for the preservation of cell therapy products Allison Hubel University of Minnesota
5-R03-EB026526-02 Hybrid decellularized extracellular matrix hydrogel for harnessing mesenchymal stem cell pro-angiogenic potential Gargi Ghosh University of Michigan at Ann Arbor
5-R01-EB022033-04 Engineering an immuno-isolating hydrogel for restoring ovarian endocrine function Ariella Shikanov University of Michigan at Ann Arbor
5-R01-EB024531-03 Computational Design, Fabrication, and Evaluation of Optimized Patient-Specific Transtibial Prosthetic Sockets Hugh Herr Massachusetts Institute of Technology
5-R03-EB024134-02 Controlling matrix metalloproteinase activity for engineered tendon formation Nathan Schiele University of Idaho
5-R21-EB026175-02 Developing Hybrids of Cardiac Tissue and Biodegradable Electronics Towards Heart Implants with On-line Monitoring and Stimulating Functions Cunjiang Yu University of Houston
4-DP2-EB020537-03 3D Printed Nano-Bionic Organs Michael Mcalpine University of Minnesota