Delivery Systems and Devices for Drugs and Biologics
The area of delivery systems and devices for drugs and biologics includes the delivery of nucleic acids, peptides, proteins, vaccines, genes, small molecules, and theranostics. Emphasis is on the engineering of new delivery vehicles that may include (but are not limited to) novel biomaterials, liposomes, micelles, nanoparticles, and dendrimers; or various delivery modalities that may include, for example, ultrasound, electroporation, implantable pumps, or stimulators. The scope of work may include, for example, development of the delivery vehicle or device itself, and proof of concept testing through preliminary in vitro and in vivo studies.
|Grant Number||Project Title||Principal Investigator||Institution|
|5-R01-EB017722-04||Efficacy and Safety of a Novel, Implantable Drug-eluting Film in Sarcoma||Yolonda Colson||Brigham And Women'S Hospital|
|1-F32-EB026916-01||Bioactive Nanoparticles for Improved Healing in Chronic Wounds||Beyza Bulutoglu||Massachusetts General Hospital|
|5-R01-EB019893-03||Cancer Stem Cell-Targeted, Silicate Prodrug Nanoparticles to Combat Recurrence||Jayanth Panyam||University of Minnesota|
|5-R21-EB025490-02||Harnessing the gap junction network for direct intracellular delivery of siRNA and chemotherapeutics||Jeanne Stachowiak||University of Texas, Austin|
|5-R01-EB020676-04||Trehalose Glycopolymers to Enhance both Pharmacokinetics and Stability of Therapeutic Proteins||Heather Maynard||University of California Los Angeles|