Emphasis is on the design and construction of tools for analyzing and controlling the function of engineered human tissues. Outcomes include but are not limited to:
- real-time, non-invasive monitoring of tissue function and cell-environment interactions
- control of spatiotemporal tissue growth through cell viability, guiding, differentiation, and migration
- design, 3D printing, and assembly of human tissues for and biomedical applications
- preservation of biological specimens, from protein solutions and cell suspensions to tissues and organs, for a variety of biomedical applications, including transplantation
The development of analytical tools and control systems for the interrogation, manipulation, and expansion of stem cells and other single cell populations is supported by the NIBIB Engineered Cells program.
This short video briefly highlights 6 cool technologies that your tax dollars have helped to fund.
Tissue engineering (also called "Regenerative Medicine") refers to the attempt to create functional human tissue from cells in a laboratory.
Research funded by the NIH at the Massachusetts Institute of Technology has resulted in the ability to provide both mouse liver function and human liver function in the same mouse. This capability enables researchers to investigate how human livers metabolize drugs, to test susceptibility to toxicity, and to demonstrate species-specific responses that typically do not show up until clinical trials.
New material promotes wound healing