Paralyzing damage in spinal cord injury is often caused by the zealous immune response to the injury. NIBIB-funded engineers have developed nanoparticles that lure immune cells away from the spinal cord, allowing regeneration that restored spinal cord function in mice.
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NIBIB-funded researchers use passive cavitation imaging, an ultrasound imaging technique, to create an image and estimate the amount of drug that crossed the blood-brain barrier to reach a specific location in the brain.
NIBIB researchers have designed a nanoparticle that generates radiation-induced oxygen free radicals in the low-oxygen center of tumors, dramatically increasing tumor destruction.
An NIH-funded team at the University of Colorado (UC) has assembled a clearer picture of the molecular activity that occurs when nanoparticles injected into the body are marked for immune system attack.
Researchers have developed nanorobotic agents that can navigate through the bloodstream to administer a drug by targeting the active cancerous cells of tumors.
New research shows, a biodegradable nanoparticle acts like a Trojan horse, hiding an allergen in a friendly shell, to convince the immune system not to attack.