Creating Biomedical Technologies to Improve Health


Antonio Sastre, Ph.D.

Antonio Sastre
Program Director

BG 2DEM RM 234 6707 Democracy Blvd Bethesda MD 20817



Dr. Antonio Sastre is a Program Director and Acting Deputy Director of Extramural Sciences at the NIBIB. He joined NIBIB in 2012, after five years at the Imaging and Bioengineering IRG at the NIH Center for Scientific Review as a Scientific Review Officer. In that position he was responsible for the review of applications where the imaging modalities included SPECT, PET, MRI/MRS, ultrasound, CT, photonics, image-guided surgery, CAD, image recognition algorithms, as well as hybrid approaches. In different years he was the point person for a new cross-IRG review effort for translational and clinical applications in oncology, cardiovascular, neurological and musculoskeletal diseases, and for an NCI Academic-Industrial Partnership for translation of in vivo imaging systems. In addition, he was responsible for the review of novel developments in electromagnetic imaging and technology, from the ELF range of frequencies (e.g. SERF magnetometers and source localization algorithms for magnetocardiography and magnetoencephalography), through RF/MW approaches for imaging, to recent THz imaging developments. He was involved in a broad range of application mechanisms, such as R03, conventional R21s and special R21/R33s, R01s (in several Special Emphasis Panels and rotating as the SRO of record in the Charter study section MEDI), SBIRs and STTRs, Bioengineering Research Partnerships, S10s, and P41 National Resource Center applications.

Dr. Sastre obtained his Ph.D. in applied mathematics from Cornell University, and completed NIH-sponsored postdoctoral training in neurobiology at Cornell University and in pharmacology at the Cornell Medical College. Thereafter, he spent 11 years on the full-time faculty at the Johns Hopkins University School of Medicine, with appointments in the Departments of Physiology and Neuroscience. At Johns Hopkins, he studied neural autonomic, cardiac and vascular neurotransmitter receptor and effector properties with joint radioligand and functional methods, from the molecular to the tissue level. After a number of years in the private sector, he joined the non-profit Midwest Research Institute, where he directed peer-reviewed research programs for 10 years, the last 4 years as Principal Advisor for Science. During this time Dr. Sastre's research encompassed systemic cardiac and neurophysiology and pharmacology, biomathematics, bioelectromagnetics, and autonomic nervous control of the cardiovascular system in humans, as well as the effects of selected environmental exposures and their interactions with genetic polymorphisms in degradative enzyme pathways.