Creating Biomedical Technologies to Improve Health

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Grantee News • August 19, 2014

A microfluidic device developed at Massachusetts General Hospital (MGH) may help study key steps in the process by which cancer cells break off from a primary tumor to invade other tissues and form metastases.

Press Releases • August 15, 2014
The National Institutes of Health is challenging science innovators to compete for prizes totaling up to $500,000, by developing new ways to track the health status of a single cell in complex tissue over time. The NIH Follow that Cell Challenge seeks tools that would, for example, monitor a cell in the process of becoming cancerous, detect changes due to a disease-causing virus, or track how a cell responds to treatment.
Press Releases • August 13, 2014

NIH announces winners of 2014 Undergraduate Biomedical Engineering Competition

Four undergraduate teams design creative new solutions to longstanding healthcare problems

Science Highlights • August 12, 2014
During surgery to remove brain gliomas, damage to adjacent healthy brain tissue can have significant effects on a patient’s neural function. On the other hand, if cancerous tissue is not completely removed, the tumor may grow back. To address these issues, NIBIB-funded researchers have developed an imaging system that rapidly and accurately detects a molecular marker found in brain gliomas. It promises to improve the precision of these difficult surgeries by enabling the complete removal of the tumor, while reducing residual damage to brain tissue and neural function.
Press Releases • August 11, 2014
NIBIB-supported bioengineers at Tufts University have created three-dimensional brain-like tissue that functions like and has structural features similar to tissue in the rat brain and that can be kept alive in the lab for more than two months.The tissue could provide a superior model for studying normal brain function as well as injury and disease, and could assist in the development of new treatments for brain dysfunction.
NIBIB in the News • August 11, 2014

The New York Times reports on a recent report by NIBIB-funded bioengineers at Tufts Univesrity about the creation of 3D functional, brain-like tissue that resembles the structural and functional features of rat brain tissue. Read the full story at

NIBIB in the News • August 11, 2014

NBC News reports on a new kind of brain-like tissue created by NIBIB-funded bioengineers at Tufts University that can sustain lab-grown neurons for weeks on end, so well that the neurons respond to hard knocks the way an actual brain would. Read the full story at

NIBIB in the News • August 11, 2014

NIBIB-funded Bioengineers at Tufts University have constructed 3D brain-like tissue that can live for more than two months and allows real-time research on brain trauma, disease and recovery. Read the full story at

Science Highlights • August 8, 2014
Researchers have created a genetically engineered mouse that allows them to observe the movement of molecules in the brain that may be involved in the formation of memories. The transgenic mouse carries a fluorescently labeled messenger RNA (mRNA) that can be visualized in cells without disrupting normal physiological processes. This new genetic tool allows the observation of gene expression in real time in neurons where the movement of the fluorescently labeled beta-actin mRNA is providing clues to the molecular changes that take place in the brain to form and store memories.
Grantee News • August 8, 2014

Building upon previous research, scientists at the University of California, San Diego School of Medicine and Veteran’s Affairs San Diego Healthcare System report that neurons derived from human induced pluripotent stem cells (iPSC) and grafted into rats after a spinal cord injury produced cells with tens of thousands of axons extending virtually the entire length of the animals’ central nervous system. Read more at UC San Diego