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Bioengineers have combined standard microscopy, infrared light, and artificial intelligence to assemble digital biopsies that identify important molecular characteristics of cancer biopsy samples.

Grace C.Y. Peng, Ph.D., Director of the NIBIB Program in Mathematical Modeling, Simulation and Analysis, has been elected to the American Institute for Medical and Biological Engineering (AIMBE College of Fellows).

Researchers have used an ultrasound technique they pioneered a decade ago -- electromechanical wave imaging (EWI) -- to accurately localize atrial and ventricular cardiac arrhythmias in adult patients in a double-blinded clinical study. They evaluated the accuracy of EWI for localization of various arrhythmias in all four chambers of the heart prior to catheter ablation: the results showed that EWI correctly predicted 96% of arrhythmia locations as compared with 71% for 12-lead ECGs.

Whether it is a drug-resistant strain of bacteria, or cancer cells that no longer react to the drugs intended to kill them, diverse mutations make cells resistant to chemicals, and 'second generation' approaches are needed. Now, a team of engineers may have a way to predict which mutations will occur in people, creating an easier path to create effective pharmaceuticals.

With the help of photolithography and programmable DNA, researchers have created a new technique that can rapidly 'print' two-dimensional arrays of cells and proteins that mimic a wide variety of cellular environments in the body. This technique could help scientists develop a better understanding of the complex cell-to-cell messaging that dictates a cell's final fate.

Biological engineers have created a multitissue model that lets them study the relationships between different organs and the immune system on a microfluidic chip seeded with human cells. With this 'organs-on-a-chip' model, they could explore the role of immune cells in ulcerative colitis and other inflammatory diseases.

Ranu Jung designs neural engineering projects that drive the process of transforming basic discoveries into clinical applications. In this interview she explains how collaborative projects can at once advance the understanding of the brain and the development of medical devices.

Bioengineers have created a 3D-printed scaffold designed to regenerate complex tissues composed of multiple layers of cells with different biological and mechanical properties.

NIH has granted Sandia $6 million to build the prototype medical device that would make magnetoencephalography (MEG) — a type of noninvasive brain scan — more comfortable, more accessible and potentially more accurate.