Careers

Research Project Title: Understanding Cellular and Tissue Molecular Mechanical Regulation for Self-organization.

Position Description: The National Institute of Biomedical Imaging and Bioengineering (NIBIB) is seeking exceptional candidates for a Post-Doctoral Fellow position in the Intramural Research Program, in the newly established Section on Mechanobiology.

The focus of this position is on the development and use of advanced Atomic Force Microscopy (AFM) technologies for cellular and tissue mechanics work, with opportunities to work on high spatio-temporal resolution AFM and confocal fluorescent microscopies, image analysis, and mathematical modeling.

The Section on Mechanobiology seeks to elucidate the molecular-mechanical regulation of two important biological processes: (i) the molecular-mechanical regulation of the actomyosin cortex of melanoma cells and the solid tumor microenvironment for deciphering self-organization in cancer biology, and (ii) the anisotropic mechanical properties of developmental and mature inner ear sensory and non-sensory epithelial tissues using a novel noncontact AFM approach. The lab also develops new AFM methodologies to study fast multiparametric and multidimensional cellular and tissue processes, and advances the state-of the-art AFM imaging methods for high spatio-temporal and quantitative nanomechanical mapping.

Qualifications: The ideal candidate will have a Ph.D. degree in cellular biology, biophysics, biomedical or mechanical engineering, or related discipline, with some background in molecular cell biology and developmental biology, and a demonstrated ability to work in a multidisciplinary and diverse team. We are seeking a highly motivated individual who has a demonstrated record of productivity and success in scientific and engineering projects. The candidate must have experience on cellular and tissue mechanics, tissue culture, AFM imaging, optical imaging, and programming for data analysis (preferably MATLAB or R) and/or experimental devices control (preferably LabVIEW).

Position Location: Bethesda, Maryland (NIH main campus)

To Apply: Salary is determined by the NIH stipend level for Post-Doctoral Trainees and Fellows. Applicants are invited to submit a curriculum vitae including a list of publications, a maximum one-page summary of research interests, and names and contact details of three referees to Dr. Cartagena-Rivera by email at alexander.cartagena-rivera@nih.gov.

The National Institutes of Health is an equal opportunity employer. The NIH is dedicated to building a diverse community in its training and employment programs.

Research and Clinical Fellowships in the Imaging Sciences Training Program

The Imaging Sciences Training Program (ISTP), at the National Institutes of Health, jointly sponsored by Radiology and Imaging Sciences (RAD) in the Clinical Center and the Intramural Research Program of the National Institute of Biomedical Imaging and Bioengineering (NIBIB), is accepting applications for one to two-year fellowship positions on a rolling admission basis. This program provides an excellent opportunity for individuals who plan a research career in imaging and biomedical sciences.

This ISTP provides opportunities in clinical, translational and basic imaging research available in Radiology and Imaging Sciences, Nuclear Medicine, Positron Emission Tomography, Interventional Radiology Laboratory and Molecular and Cellular Imaging. The program spans research in all aspects of clinical and basic imaging sciences. Applicants can choose to work in research areas including: neuroimaging, interventional, oncological, vascular, metabolic imaging and computer-aided diagnosis using various imaging techniques. There are bench-to-bedside research opportunities in MRI/MRS, MR microscopy, PET radiochemistry, contrast agent development, cellular and molecular imaging, high intensity focused ultrasound, and targeted drug delivery, and innovative image processing and visualization algorithms. Qualified applicants will also be able to have clinical exposure to a unique research patient population found at the NIH. Fellows in the ISTP will have access to state-of-the-art imaging and computer facilities dedicated to research found in the Clinical Center, In Vivo NMR Research Center, and various basic science laboratories. Collaboration with imaging scientists on the NIH campus will be encouraged.

Applicants should hold an MD, MD/PhD or PhD degree and should have completed training in radiology, nuclear medicine, biomedical engineering or a related area of the imaging sciences. Applications from individuals currently in U.S. residency programs may also be considered for research fellowship positions. Foreign graduates can also be considered for the Fogarty Visiting Fellows Program. U.S. citizenship or permanent residency is required for this full-time equivalent appointment. Salary will vary depending upon qualifications including number of years of post-residency or graduate training. NIH also provides a generous benefits package. NIH is dedicated to building a diverse community in its training and employment programs.

Candidates should submit a curriculum vitae, at least three letters of reference and a preliminary statement concerning their area of research interest to:

Dr. Joseph A. Frank
c/o Ms. Cassandra Smith
Radiology and Imaging Sciences
Building 10 Room B1N256
10 Center Drive MSC 1074
Bethesda, Maryland 20892-1074
E-mail: smithc4@cc.nih.gov

Additional information can be found at the Imaging Sciences Training Program website.

NIH is an equal opportunity employer.

Intravital Microscope Postdoctoral Fellow Position

The Laboratory of Molecular Imaging and Nanomedicine (LOMIN) at the National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH) is looking for a motivated post-doctoral fellow interested in dissecting tumor microenvironment and studying nano-bio interactions of various inorganic and polymeric nanomaterials using intravital microscopy.

Basic requirement:

1. Sound knowledge in biomedical sciences
2. Proficiency in animal handling
3. Proficiency in fluorescence microscopy, especially intravital microscopy
4. Proficiency in various animal models for intravital microscopy such as dorsal chamber model, cranial chamber model and ear model.

Expertise in nanomedicine is preferred by not mandatory.  Interested candidates please contact Dr. Xiaoyuan (Shawn) Chen at shawn.chen@nih.gov.

The NIH is dedicated to building a diverse community in its training and employment programs.

Multiple Postdoctoral Positions at the Laboratory of Molecular Imaging and Nanomedicine (LOMIN)

The research program in the Laboratory of Molecular Imaging and Nanomedicine (LOMIN) at the National Institute of Biomedical Imaging and Bioengineering (NIBIB) emphasizes the development of molecular imaging tools for better understanding of biology, early diagnosis of disease, monitoring therapy response, and guiding drug discovery/development. LOMIN places special emphasis on high-sensitivity nanosensors for biomarker detection and theranostic nanomedicine for imaging, gene and drug delivery, and monitoring of treatment.

We are constantly seeking highly motivated recent graduates as postdoctoral fellows with expertise in one or more of the following:

1. Peptide and oligonucleotide synthesis
2. Protein and antibody engineering
3. Cellular and molecular biology
4. Nanoparticles for drug and gene delivery
5. Bioconjugation chemistry (with organic synthesis background)
6. PET radiochemistry (especially methodology development)
7. Nanosensors for biomarker detection (including point-of-care diagnostics)
8. Proteomics at nano-biointerface
9. Small animal handling and multimodality imaging
10. Image quantification and biomedical engineering
11. Smart nanomaterials as theranostics (diagnostics, imaging, and therapy)
12. Translational research (CMC, pharmacology, GLP toxicity, and IND compiling)

If you are interested, please send a letter of application, curriculum vitae, and names of three references to Dr. Xiaoyuan (Shawn) Chen at shawn.chen@nih.gov. All qualified candidates are encouraged to apply; US citizens and permanent residents will be given priority. Due to the high number of applications, only those with matching qualifications will be contacted.