Careers

Field: Immunology, Epigenetics, Regenerative Medicine, Trauma Medicine

Research Project Title: Genetic Understanding and Manipulation of Immune Responses to Biomaterials

Position Description: The National Institute of Biomedical Imaging and Bioengineering (NIBIB) is seeking candidates for a Post-Doctoral Fellow position in the Intramural Research Program, in the Section on Immuno-Engineering.

This position will work at the intersection of immunology and engineering to analyze biological responses to medical device implantation and develop new technologies to promote device integration and tissue regeneration. Work will focus on characterizing immune responses to materials with the opportunity to work with next-generation high-color flow cytometers and the vast microscopy knowledge available at NIBIB.  Will also work closely with collaborating immunologists in other NIH institutes and with muscle trauma researchers at Walter Reed National Military Medical Center, who will help with functional regeneration testing. The Section on Immuno-Engineering focuses on immune reactions to medical devices and regenerative therapeutics to determine biologic mechanisms of immune responses to biomaterials in order to   then leverage/modulate those to promote device integration and tissue regeneration. Candidates would be responsible for conducting studies to understand the basic molecular mechanisms of the local and systemic immune response to biomaterials and medical devices, focusing on innate immune activation and differentiation.

Qualifications: The applicant must have a Ph.D. in Molecular Biology, Immunology, or related discipline. The applicant must display strong technical experience with bisulfite sequencing and/or ChIP-sequencing, along with exposure standard techniques such as qRT-PCR and flow cytometry. Experience with animal modeling is preferred. Due to the interdisciplinary nature of the research, any interested applicants should be open to learning new techniques, especially in the field of trauma medicine and biomaterial therapeutics.

To Apply: Interested applicants should send their CV along with a one-page research statement (past/current/future) and the names and email addresses of 3 references to Dr. Kaitlyn Sadtler at kaitlyn.sadtler@nih.gov.

Position includes salary and benefits in line with NIH standard levels for postdoctoral fellows.

The NIH is dedicated to building a diverse community in its training and employment programs. The United States Government does not discriminate in employment on the basis of race, color, religion, sex (including pregnancy and gender identity), national origin, political affiliation, sexual orientation, marital status, disability, genetic information, age, membership in an employee organization, retaliation, parental status, military service, or other non-merit factor.

CONTACT: Dr. Kaitlyn Sadtler, PhD

Position Description:

The National Institute of Biomedical Imaging and Bioengineering (NIBIB), a part of the National Institutes of Health (NIH), has an opening for a highly motivated senior scientist in the Laboratory of Molecular Imaging and Nanomedicine (LOMIN). LOMIN has been established to develop in vitro diagnostics, in vivo imaging techniques, and nanobiotechnology with an emphasis on molecular imaging tools and drug and gene delivery techniques. The staff scientist will be responsible for managing the lab.

Qualifications:

The desired applicants will have a Ph.D. (preferably in biochemistry, pharmaceutical sciences, life sciences, or biomedical engineering) and postdoctoral experience with proficiency in designing research projects and managing labs. Detailed knowledge of molecular imaging probes and nanomedicine is mandatory. The ability to design and perform scientific work independently and collaboratively is required. Candidates must be able to thrive in a fast-paced environment. Experience with chemistry and radiochemistry, cell culture, animal handling, small animal imaging, and translational research is highly preferred but not required. Motivation and drive to work hard and learn new skills are also important.

The candidate may be a U.S. citizen, resident alien, or non-resident alien eligible to obtain a valid employment authorization visa. Salary is commensurate with experience. A full package of benefits is available. The successful candidate will need to complete an on-site interview process and deliver a brief research presentation.

How to Apply:

The applicant must submit a CV, a one-page summary of previous research, and provide the contact information for three references to Dr. Shawn Chen at Shawn.Chen@nih.gov.

Please write "LOMIN Staff Scientist" in the subject header. Applications for this position will be accepted from 11/05/2019 to 01/05/2020.

The NIH is dedicated to building a diverse community in its training and employment programs.

The United States Government does not discriminate in employment on the basis of race, color, religion, sex (including pregnancy and gender identity), national origin, political affiliation, sexual  orientation, marital status, disability, genetic information, age, membership in an employee organization, retaliation, parental status, military service, or other non-merit factor.

Research Project Title: Understanding Cellular and Tissue Molecular Mechanical Regulation for Self-organization.

Position Description: The National Institute of Biomedical Imaging and Bioengineering (NIBIB) is seeking exceptional candidates for a Post-Doctoral Fellow position in the Intramural Research Program, in the newly established Section on Mechanobiology.

The focus of this position is on the development and use of advanced Atomic Force Microscopy (AFM) technologies for cellular and tissue mechanics work, with opportunities to work on high spatio-temporal resolution AFM and confocal fluorescent microscopies, image analysis, and mathematical modeling.

The Section on Mechanobiology seeks to elucidate the molecular-mechanical regulation of two important biological processes: (i) the molecular-mechanical regulation of the actomyosin cortex of melanoma cells and the solid tumor microenvironment for deciphering self-organization in cancer biology, and (ii) the anisotropic mechanical properties of developmental and mature inner ear sensory and non-sensory epithelial tissues using a novel noncontact AFM approach. The lab also develops new AFM methodologies to study fast multiparametric and multidimensional cellular and tissue processes, and advances the state-of the-art AFM imaging methods for high spatio-temporal and quantitative nanomechanical mapping.

Qualifications: The ideal candidate will have a Ph.D. degree in cellular biology, biophysics, biomedical or mechanical engineering, or related discipline, with some background in molecular cell biology and developmental biology, and a demonstrated ability to work in a multidisciplinary and diverse team. We are seeking a highly motivated individual who has a demonstrated record of productivity and success in scientific and engineering projects. The candidate must have experience on cellular and tissue mechanics, tissue culture, AFM imaging, optical imaging, and programming for data analysis (preferably MATLAB or R) and/or experimental devices control (preferably LabVIEW).

Position Location: Bethesda, Maryland (NIH main campus)

To Apply: Salary is determined by the NIH stipend level for Post-Doctoral Trainees and Fellows. Applicants are invited to submit a curriculum vitae including a list of publications, a maximum one-page summary of research interests, and names and contact details of three referees to Dr. Cartagena-Rivera by email at alexander.cartagena-rivera@nih.gov.

The National Institutes of Health is an equal opportunity employer. The NIH is dedicated to building a diverse community in its training and employment programs.

Research and Clinical Fellowships in the Imaging Sciences Training Program

The Imaging Sciences Training Program (ISTP), at the National Institutes of Health, jointly sponsored by Radiology and Imaging Sciences (RAD) in the Clinical Center and the Intramural Research Program of the National Institute of Biomedical Imaging and Bioengineering (NIBIB), is accepting applications for one to two-year fellowship positions on a rolling admission basis. This program provides an excellent opportunity for individuals who plan a research career in imaging and biomedical sciences.

This ISTP provides opportunities in clinical, translational and basic imaging research available in Radiology and Imaging Sciences, Nuclear Medicine, Positron Emission Tomography, Interventional Radiology Laboratory and Molecular and Cellular Imaging. The program spans research in all aspects of clinical and basic imaging sciences. Applicants can choose to work in research areas including: neuroimaging, interventional, oncological, vascular, metabolic imaging and computer-aided diagnosis using various imaging techniques. There are bench-to-bedside research opportunities in MRI/MRS, MR microscopy, PET radiochemistry, contrast agent development, cellular and molecular imaging, high intensity focused ultrasound, and targeted drug delivery, and innovative image processing and visualization algorithms. Qualified applicants will also be able to have clinical exposure to a unique research patient population found at the NIH. Fellows in the ISTP will have access to state-of-the-art imaging and computer facilities dedicated to research found in the Clinical Center, In Vivo NMR Research Center, and various basic science laboratories. Collaboration with imaging scientists on the NIH campus will be encouraged.

Applicants should hold an MD, MD/PhD or PhD degree and should have completed training in radiology, nuclear medicine, biomedical engineering or a related area of the imaging sciences. Applications from individuals currently in U.S. residency programs may also be considered for research fellowship positions. Foreign graduates can also be considered for the Fogarty Visiting Fellows Program. U.S. citizenship or permanent residency is required for this full-time equivalent appointment. Salary will vary depending upon qualifications including number of years of post-residency or graduate training. NIH also provides a generous benefits package. NIH is dedicated to building a diverse community in its training and employment programs.

Candidates should submit a curriculum vitae, at least three letters of reference and a preliminary statement concerning their area of research interest to:

Dr. Joseph A. Frank
c/o Ms. Cassandra Smith
Radiology and Imaging Sciences
Building 10 Room B1N256
10 Center Drive MSC 1074
Bethesda, Maryland 20892-1074
E-mail: smithc4@cc.nih.gov

Additional information can be found at the Imaging Sciences Training Program website.

NIH is an equal opportunity employer.