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Tiny generators turn body motion into weight control and wound-healing therapies

Science Highlights • January 17, 2019
Although electrical stimulation has therapeutic potential for various disorders and conditions, ungainly power sources have hampered practical applications. Now bioengineers have developed implantable and wearable nanogenerators from special materials that create electrical pulses when compressed by body motions. The pulses controlled weight gain and enhanced healing of skin wounds in rat models.

Sugary stent eases suturing of blood vessels

Grantee News • January 16, 2019

A team has concocted a sugar-heavy stent to reduce the margin of error in a delicate surgical procedure. Read more at Nebraska Today.

Bioactive scaffolds guide the way to sore knee relief, cartilage repair

Science Highlights • January 14, 2019
NIBIB-funded researchers have developed a 3D-printed scaffold coated in aggrecan, a native cartilage component, to improve the regeneration of cartilage tissue in joints. The scaffold was combined with a common microfracture procedure and tested in rabbits. The University of Maryland researchers found the combination of the implant and microfracture procedure to be ten times more effective than microfracture alone. Microfracture alone is the standard therapy currently.

Scope advance reveals first look through all cortical layers of awake brain

Grantee News • January 14, 2019

Improvements in three-photon microscopy have allowed scientists to see activity in all layers of the visual cortex and the 'subplate' below. Read more at MIT News.

Bruce J. Tromberg, Ph.D., appointed Director of the National Institute of Biomedical Imaging and Bioengineering

Science Highlights • January 7, 2019
During an official swearing in ceremony on Jan. 7, 2019, at the National Institutes of Health in Bethesda, Maryland, NIH Director Francis Collins officially welcomed Bruce Tromberg to assume the post of Director of the National Institute of Biomedical Imaging and Bioengineering.

Artificial intelligence system learns to diagnose, classify intracranial hemorrhage

Grantee News • December 27, 2018

A team of investigators has developed a system using artificial intelligence to quickly diagnose and classify brain hemorrhages and to provide the basis of its decisions from relatively small image datasets. Read more from Mass General News.

Tiny implantable device short-circuits hunger pangs, aids weight loss

Grantee News • December 19, 2018

New battery-free, easily implantable weight-loss devices developed by engineers could offer a promising new weapon for battling the bulge. Read more from Medical Express.

Shrinking objects to the nanoscale

Grantee News • December 17, 2018

Researchers have invented a new way to fabricate nanoscale 3D objects of nearly any shape. They can also pattern the objects with a variety of useful materials, including metals, semiconducting quantum dots, and DNA. Read more from MIT News.

Wearable ultrasound patch penetrates the skin to measure blood pressure

Science Highlights • December 14, 2018
NIBIB-funded researchers are literally breaking barriers using ultrasound waves emitted from a flexible patch to accurately measure central blood pressure and help detect cardiovascular problems earlier. For a while now, smart, wearable devices have had the ability to capture how many steps we take in a day or measure our heart rate, but researchers are starting to take it a step further.

Ingestible capsule can be controlled wirelessly

Grantee News • December 14, 2018

Researchers have designed an ingestible capsule that can be controlled using Bluetooth wireless technology. Their capsule, which can be customized to deliver drugs, sense environmental conditions, or a combination of those functions, can reside in the stomach for at least a month, transmitting information and responding to instructions from a user's smartphone. Read more at MIT News.

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