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New cell therapy aids heart recovery -- without implanting cells

Grantee News • April 24, 2018

Medical researchers have designed a creative new approach to help injured hearts regenerate by applying extracellular vesicles secreted by cardiomyocytes rather than implanting the cells. The study shows that the cardiomyocytes derived from human pluripotent stem cells (derived in turn from a small sample of blood) could be a powerful, untapped source of therapeutic microvesicles that could lead to safe and effective treatments of damaged hearts. Read more at Columbia University Engineering News.

Chip-based blood test for multiple myeloma could make bone biopsies a relic of the past

Grantee News • April 23, 2018

A new research effort has resulted in a low-cost, reliable blood test that uses a small plastic chip about the size of a credit card that can deliver the same diagnostic information as a bone biopsy -- but using a simple blood draw instead. Read more at University of Kansas News.

Reusable glucose meter paired with smartphone for on-the-go monitoring

Science Highlights • April 19, 2018
Bioengineers at the University of California, San Diego, with funding from NIBIB, have designed a glucose meter system built into a smartphone case, along with a smartphone app to present the results. The researchers developed the new device, called GlucPhone, with convenience and portability in mind.

Turning the light switch on to treat chronic pain

April 16, 2018
In a study published in the Nov. 22, 2017, issue of Scientific Reports, researchers with funding from NIBIB reported the first use of optogenetics to reduce bladder pain. Their results in mice offer hope for much needed human therapy.

Fluorescent dye could enable sharper biological imaging

Grantee News • April 12, 2018

Researchers have now taken a major step toward making short-wave infrared (SWIR) imaging widely available. Read more at MIT News.

Monitor detects dangerously low white blood cell levels

Grantee News • April 4, 2018

Researchers have now developed a portable device that could be used to monitor patients' white blood cell levels at home, without taking blood samples. Watch the video here.

NIBIB-funded bioengineers develop promising technique to build tracheas for implantation

Science Highlights • April 4, 2018
NIBIB-funded researchers have developed a strategy to engineer multi-tissue tracheas that have a cartilage structure, moist lining, and blood vessels similar to a natural trachea. In a study in the Feb. 14, 2018, issue of Advanced Science, they implanted the engineered tissue under the skin of mice, where the blood vessels showed signs of connecting with surrounding tissue.

Thermo-chemotherapy combo eradicates primary and metastatic tumors in mice

Science Highlights • April 4, 2018
Bioengineers at the National Institute of Biomedical Imaging and Bioengineering (NIBIB) have developed a smart anti-cancer nanoparticle with precisely targeted tumor-killing activity superior to previous technologies.

Early stimulation improves performance of bioengineered human heart cells

Press Releases • April 4, 2018
Researchers are now able to use induced pluripotent stem cells (iPSC) to form a model of human adult-like cardiac muscle by introducing electric and mechanical stimulation at an early stage. Since this muscle is similar to the adult heart, it could serve as a better model for testing the effects of drugs and toxic substances than current tissue-engineered heart models.

Smart devices being looked at to monitor blood pressure, stroke

NIBIB in the News • April 3, 2018
Researchers from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) are looking at using smartphones to monitor a person’s blood pressure and smartwatches to look for signs of a stroke.

Read more at Life Science Daily.

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