The PET Radiochemistry and Imaging Core Facility develops novel methods for incorporating radionuclides and fluorophores into molecules for the study of biologically important processes. All of our projects are in support of principal investigator-initiated research. We seek to collaborate with clinical and biological investigators who share our goal of providing new imaging tools for clinical studies and the study of biological processes. Our research efforts are driven by a desire to improve understanding of human biology and disease and to generate tools that have clinical application. We have produced probes with applications to many important biological processes, including inflammation, metabolism, proliferation, angiogenesis, metastasis, lymphogenesis, and apoptosis.