Alexander Cartagena-Rivera

headshot of Alexander Cartagena-Rivera
Alex
Cartagena-Rivera
Ph.D.
Investigator (Tenure-Track)
BG 35A RM 1E614D
35A Convent Dr
Bethesda, MD 20892
Biography

Dr. Alexander X. Cartagena-Rivera received a bachelor’s degree in Mechanical Engineering from the University of Puerto Rico at Mayagüez in 2010. Then he was a graduate student and research assistant in the lab of Prof. Arvind Raman at Purdue University. He received a Ph.D. in Mechanical Engineering from Purdue University in 2014. He accepted a Post-Doctoral IRTA Fellowship position in the lab of Dr. Richard S. Chadwick in the Section on Auditory Mechanics with the National Institute on Deafness and Other Communication Disorders at the National Institutes of Health in 2014. Dr. Cartagena-Rivera accepted a Tenure-Track Earl Stadtman Investigator position with the National Institute of Biomedical Imaging and Bioengineering (NIBIB) in 2019. He is now chief of NIBIB’s Section on Mechanobiology, where he and his lab staff continue work on understanding cellular and tissue molecular-mechanical regulation and development of advanced atomic force microscopy technologies for cancer biology and hearing research. In 2019 he received the prestigious NIH Distinguished Scholars Program award. His research interests lie in diverse and multidisciplinary fields including biomedical engineering, biophysics, fluid mechanics, soft matter, micro/nanomechanics, hearing mechanics, cellular biology, and living cells and viruses mechanics determined using the atomic force microscope in physiologically relevant conditions.

Research Interests
  • Understanding the molecular-mechanical regulation of the actomyosin cortex of cancer cells and the solid tumor microenvironment (primary and metastatic) for deciphering self-organization in cancer biology.
  • Understanding the anisotropic mechanical properties of developmental and mature inner ear sensory and non-sensory epithelial tissues using a novel noncontact AFM approach.
  • Developing new AFM methodologies to study fast multiparametric and multidimensional cellular and tissue processes.
  • Advancing the state-of-the-art AFM imaging methods for high spatio-temporal, multifrequency, and quantitative nanomechanical mapping.
Publications
Katsuno TBelyantseva IACartagena-Rivera AXOhta KCrump SMPetralia RSOno KTona RImtiaz ARehman AKiyonari HKaneko MWang YXAbe TIkeya MFenollar-Ferrer CRiordan GPWilson EAFitzgerald TSSegawa KOmori KIto JFrolenkov GIFriedman TBKitajiri SI
JCI Insight
2019 Jun 20

Cartagena-Rivera AXLe Gal SRichards KVerpy EChadwick RS
Sci Adv
2019 Feb


Efremov YMCartagena-Rivera AXAthamneh AIMSuter DMRaman A
Nat Protoc
2018 Oct

Logue JSCartagena-Rivera AXChadwick RS
Oncogene
2018 Apr

Van Itallie CMTietgens AJAponte AGucek MCartagena-Rivera AXChadwick RSAnderson JM
J. Cell. Sci.
2018 Feb 02

Cartagena-Rivera AXLogue JSWaterman CMChadwick RS
Biophys. J.
2016 Jun 07

Athamneh AICartagena-Rivera AXRaman ASuter DM
Biophys. J.
2015 Oct 06

Logue JSCartagena-Rivera AXBaird MADavidson MWChadwick RSWaterman CM
Elife
2015 Jul 11