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Emilios K Dimitriadis

Emilios Dimitriadis
Emilios K Dimitriadis ,
Ph.D.
Staff Scientist
Labs/Section:
301-435-1952
dimitre@mail.nih.gov
Research Interests

Expertise in:

  • Mathematical modeling of biophysical systems
  • Atomic force microscopy
  • Analytical ultracentrifugation

Research Interests:

  • Auditory mechanics
  • Protein adsorption on lipid bilayers
  • Imaging and characterization of protein-DNA complexes
Publications
Defining essential charged residues in fibril formation of a lysosomal derived N-terminal α-synuclein truncation.
McGlinchey RPRamos SDimitriadis EKWilson CBLee JC
Nat Commun
2025 Apr 23

Perivascular cells function as key mediators of mechanical and structural changes in vascular capillaries.
Franca CMLima Verde MESilva-Sousa ACMansoorifar AAthirasala ASubbiah RTahayeri ASousa MFraga MAVisalakshan RMDoe ABeadle KFinley MDimitriadis EBays JUroz MYamada KMChen CBertassoni LE
Sci Adv
2025 Jan 10

HIV-1 Integrase Assembles Multiple Species of Stable Synaptic Complex Intasomes That Are Active for Concerted DNA Integration In vitro.
Li MYang RChen XWang HGhirlando RDimitriadis EKCraigie R
J Mol Biol
2024 May 15

A novel cysteine-rich adaptor protein is required for mucin packaging and secretory granule stability in vivo.
Zhang LMuirhead KJSyed ZADimitriadis EKTen Hagen KG
Proc Natl Acad Sci U S A
2024 Feb 06

Sulfated endospermic nanocellulose crystals prevent the transmission of SARS-CoV-2 and HIV-1.
Carvajal-Barriga EJFitzgerald WDimitriadis EKMargolis LFields RD
Sci Rep
2023 Apr 28

Sulfated endospermic nanocellulose crystals prevent the transmission of SARS-CoV-2 and HIV-1.
Barriga EJCFitzgerald WDimitriadis EKMargolis LFields RD
Res Sq
2022 Oct 28

A phage-encoded nucleoid associated protein compacts both host and phage DNA and derepresses H-NS silencing.
Son BPatterson-West JArroyo-Mendoza MRamachandran RIben JRZhu JRao VDimitriadis EKHinton DM
Nucleic Acids Res
2021 Sep 20

Tyrosinase Nanoparticles: Understanding the Melanogenesis Pathway by Isolating the Products of Tyrosinase Enzymatic Reaction.
Varghese PKAbu-Asab MDimitriadis EKDolinska MBMorcos GPSergeev YV
Int J Mol Sci
2021 Jan 13

Intrinsic elasticity of nucleosomes is encoded by histone variants and calibrated by their binding partners.
Melters DPPitman MRakshit TDimitriadis EKBui MPapoian GADalal Y
Proc Natl Acad Sci U S A
2019 Nov 26

Durotaxis by Human Cancer Cells.
DuChez BJDoyle ADDimitriadis EKYamada KM
Biophys J
2019 Feb 19

Membrane-associated human tyrosinase is an enzymatically active monomeric glycoprotein.
Kus NJDolinska MBYoung KLDimitriadis EKWingfield PTSergeev YV
PLoS One
2018

Macrophages Shed Excess Cholesterol in Unique Extracellular Structures Containing Cholesterol Microdomains.
Jin XDimitriadis EKLiu YCombs CAChang JVarsano NStempinski EFlores RJackson SNMuller LWoods ASAddadi LKruth HS
Arterioscler Thromb Vasc Biol
2018 Jul

Microscale mapping of extracellular matrix elasticity of mouse joint cartilage: an approach to extracting bulk elasticity of soft matter with surface roughness.
Chandran PLDimitriadis EKMertz ELHorkay F
Soft Matter
2018 Apr 18

HIV Tat protein and amyloid-β peptide form multifibrillar structures that cause neurotoxicity.
Hategan ABianchet MASteiner JKarnaukhova EMasliah EFields ALee MHDickens AMHaughey NDimitriadis EKNath A
Nat Struct Mol Biol
2017 Apr

A New Noncoding RNA Arranges Bacterial Chromosome Organization.
Qian ZMacvanin MDimitriadis EKHe XZhurkin VAdhya S
mBio
2015 Aug 25

Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network.
Artym VVSwatkoski SMatsumoto KCampbell CBPetrie RJDimitriadis EKLi XMueller SCBugge THGucek MYamada KM
J Cell Biol
2015 Feb 02

Chromatin decompaction by the nucleosomal binding protein HMGN5 impairs nuclear sturdiness.
Furusawa TRochman MTaher LDimitriadis EKNagashima KAnderson SBustin M
Nat Commun
2015 Jan 22

DNA nanoparticles with core-shell morphology.
Chandran PLDimitriadis EKLisziewicz JSperansky VHorkay F
Soft Matter
2014 Oct 14

CENP-A octamers do not confer a reduction in nucleosome height by AFM.
Walkiewicz MPDimitriadis EKDalal Y
Nat Struct Mol Biol
2014 Jan

Cell-cycle-dependent structural transitions in the human CENP-A nucleosome in vivo.
Bui MDimitriadis EKHoischen CAn EQuénet DGiebe SNita-Lazar ADiekmann SDalal Y
Cell
2012 Jul 20

The linker of the interferon response factor 3 transcription factor is not unfolded.
Shukla HVaitiekunas PMajumdar AKDragan AIDimitriadis EKKotova SCrane-Robinson CPrivalov PL
Biochemistry
2012 Aug 14

Galactose repressor mediated intersegmental chromosomal connections in Escherichia coli.
Qian ZDimitriadis EKEdgar REswaramoorthy PAdhya S
Proc Natl Acad Sci U S A
2012 Jul 10

Measurement of plasma volume using fluorescent silica-based nanoparticles.
Eisner COw HYang TJia ZDimitriadis ELi LWang KBriggs JLevine MSchnermann JEspey MG
J Appl Physiol (1985)
2012 Feb

Probing Interactions between Aggrecan and Mica Surface by the Atomic Force Microscopy.
Chandran PLDimitriadis EKBasser PJHorkay F
J Polym Sci B Polym Phys
2010 Dec 15

Tetrameric organization of vertebrate centromeric nucleosomes.
Dimitriadis EKWeber CGill RKDiekmann SDalal Y
Proc Natl Acad Sci U S A
2010 Nov 23

Retinoschisin (RS1) interacts with negatively charged lipid bilayers in the presence of Ca2+: an atomic force microscopy study.
Kotova SVijayasarathy CDimitriadis EKIkonomou LJaffe HSieving PA
Biochemistry
2010 Aug 24

Nucleoprotein intermediates in HIV-1 DNA integration visualized by atomic force microscopy.
Kotova SLi MDimitriadis EKCraigie R
J Mol Biol
2010 Jun 11

Organization of membrane motor in outer hair cells: an atomic force microscopic study.
Sinha GPSabri FDimitriadis EKIwasa KH
Pflugers Arch
2010 Feb

Initial stages of V(D)J recombination: the organization of RAG1/2 and RSS DNA in the postcleavage complex.
Grundy GJRamón-Maiques SDimitriadis EKKotova SBiertümpfel CHeymann JBSteven ACGellert MYang W
Mol Cell
2009 Jul 31

Spherical indentation of soft matter beyond the Hertzian regime: numerical and experimental validation of hyperelastic models.
Lin DCShreiber DIDimitriadis EKHorkay F
Biomech Model Mechanobiol
2009 Oct

The influence of cochlear shape on low-frequency hearing.
Manoussaki DChadwick RSKetten DRArruda JDimitriadis EKO'Malley JT
Proc Natl Acad Sci U S A
2008 Apr 22

Gal repressor-operator-HU ternary complex: pathway of repressosome formation.
Roy SDimitriadis EKKar SGeanacopoulos MLewis MSAdhya S
Biochemistry
2005 Apr 12

Determination of elastic moduli of thin layers of soft material using the atomic force microscope.
Dimitriadis EKHorkay FMaresca JKachar BChadwick RS
Biophys J
2002 May

Arterial wall properties and Womersley flow in Fabry disease.
Moore DFAltarescu GPursley RCampia UPanza JADimitriadis ESchiffmann R
BMC Cardiovasc Disord
2002