Jiji Chen

Jiji Chen
Jiji
Chen
Ph.D.
Staff Scientist

BG 13 RM G800 13 South Dr. Bethesda MD 20892

Biography

Dr. Chen received his PhD in 2011 from Purdue University under Joseph Irudayaraj. His doctoral work utilized single molecule spectroscopy and time resolved techniques to study epigenetic modifications in single cells. He then joined the Transcription Imaging Consortium at the HHMI Janelia Research Campus to do his post-doctoral fellowship with Maxime Dahan and Robert Tjian. At Janelia, Dr. Chen co-developed the multifocus microscope – a widefield fluorescence microscope capable of imaging multiple focal planes simultaneously. He then combined multifocus microscopy with single molecule imaging to quantitatively track the interactions of transcription factors at endogenous binding elements in 3D in live cells.

Dr. Chen joined the NIH in 2016 as the Co-Operating Director of the Advanced Imaging and Microscopy Resource.

Publications

Guo MLi YSu YLambert TNogare DDMoyle MWDuncan LHIkegami RSantella ARey-Suarez IGreen DBeiriger AChen JVishwasrao HGanesan SPrince VWaters JCAnnunziata CMHafner MMohler WAChitnis ABUpadhyaya AUsdin TBBao ZColón-Ramos DLa Riviere PLiu HWu YShroff H
Nat Biotechnol
2020 Jun 29

Chen JLiu YWu BNikolaitchik OAMohan PRChen JPathak VKHu WS
Proc Natl Acad Sci U S A
2020 Mar 17

Gryder BEPomella SSayers CWu XSSong YChiarella AMBagchi SChou HCSinniah RSWalton AWen XRota RHathaway NAZhao KChen JVakoc CRShern JFStanton BZKhan J
Nat Genet
2019 Dec

Peluso EAUpdegrove TBChen JShroff HRamamurthi KS
Proc Natl Acad Sci U S A
2019 Oct 22

Liu YGong CSDai YYang ZYu GLiu YZhang MLin LTang WZhou ZZhu GChen JJacobson OKiesewetter DOWang ZChen X
Biomaterials
2019 Oct

Guo MChandris PGiannini JPTrexler AJFischer RChen JVishwasrao HDRey-Suarez IWu YWu XWaterman CMPatterson GHUpadhyaya ATaraska JWShroff H
Nat Methods
2018 Jun


Zhu GLynn GMJacobson OChen KLiu YZhang HMa YZhang FTian RNi QCheng SWang ZLu NYung BCWang ZLang LFu XJin AWeiss IDVishwasrao HNiu GShroff HKlinman DMSeder RAChen X
Nat Commun
2017 Dec 05

Zhu GMei LVishwasrao HDJacobson OWang ZLiu YYung BCFu XJin ANiu GWang QZhang FShroff HChen X
Nat Commun
2017 Nov 14

Wu YKumar ASmith CArdiel EChandris PChristensen RRey-Suarez IGuo MVishwasrao HDChen JTang JUpadhyaya ALa Riviere PJShroff H
Nat Commun
2017 Nov 13

Qian ZZhurkin VBAdhya S
Proc Natl Acad Sci U S A
2017 Nov 14

Kieffer-Kwon KRNimura KRao SSPXu JJung SPekowska ADose MStevens EMathe EDong PHuang SCRicci MABaranello LZheng YTomassoni Ardori FResch WStavreva DNelson SMcAndrew MCasellas AFinn EGregory CSt Hilaire BGJohnson SMDubois WCosma MPBatchelor ELevens DPhair RDMisteli TTessarollo LHager GLakadamyali MLiu ZFloer MShroff HAiden ELCasellas R
Mol Cell
2017 Aug 17

Normanno DBoudarène LDugast-Darzacq CChen JRichter CProux FBénichou OVoituriez RDarzacq XDahan M
Nat Commun
2015 Jul 07

Grimm JBEnglish BPChen JSlaughter JPZhang ZRevyakin APatel RMacklin JJNormanno DSinger RHLionnet TLavis LD
Nat Methods
2015 Mar

Hajj BWisniewski JEl Beheiry MChen JRevyakin AWu CDahan M
Proc Natl Acad Sci U S A
2014 Dec 09


Chen JZhang ZLi LChen BCRevyakin AHajj BLegant WDahan MLionnet TBetzig ETjian RLiu Z
Cell
2014 Mar 13