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LDMA Publications

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Magone MTSchuck P
Cornea
2024 Oct 01

Flotation Coefficient Distributions of Lipid Nanoparticles by Sedimentation Velocity Analytical Ultracentrifugation.
Zhao HSousa AASchuck P
ACS Nano
2024 Jul 16

Modulation of biophysical properties of nucleocapsid protein in the mutant spectrum of SARS-CoV-2.
Nguyen AZhao HMyagmarsuren DSrinivasan SWu DChen JPiszczek GSchuck P
Elife
2024 Jun 28

Assembly of SARS-CoV-2 nucleocapsid protein with nucleic acid.
Zhao HSyed AMKhalid MMNguyen ACiling AWu DYau WMSrinivasan SEsposito DDoudna JAPiszczek GOtt MSchuck P
Nucleic Acids Res
2024 Jun 24

Exploring Host-Guest Interactions within a 600 kDa DegP Protease Cage Complex Using Hydrodynamics Measurements and Methyl-TROSY NMR.
Harkness RWZhao HToyama YSchuck PKay LE
J Am Chem Soc
2024 Mar 27

Amyloid-β aggregates activate peripheral monocytes in mild cognitive impairment.
Juul-Madsen KParbo PIsmail ROvesen PLSchmidt VMadsen LSThyrsted JGierl SBreum MLarsen AAndersen MNRomero-Ramos MHolm CKAndersen GRZhao HSchuck PNygaard JVSutherland DSEskildsen SFWillnow TEBrooks DJVorup-Jensen T
Nat Commun
2024 Feb 09

Modulation of Biophysical Properties of Nucleocapsid Protein in the Mutant Spectrum of SARS-CoV-2.
Nguyen AZhao HMyagmarsuren DSrinivasan SWu DChen JPiszczek GSchuck P
bioRxiv
2024 Mar 22

Evaluating Moisture Migration in Schirmer Test Strips: Exploring Brand-Specific Variations and Introducing Calibration and Conversion Methods.
Magone MTSchuck P
Cornea
2024 May 01

The 5α condensate state in Ne.
Zhou BFunaki YHoriuchi HMa YGRöpke GSchuck PTohsaki AYamada T
Nat Commun
2023 Dec 11

Assembly reactions of SARS-CoV-2 nucleocapsid protein with nucleic acid.
Zhao HSyed AMKhalid MMNguyen ACiling AWu DYau WMSrinivasan SEsposito DDoudna JAPiszczek GOtt MSchuck P
bioRxiv
2023 Nov 23

Diversity of short linear interaction motifs in SARS-CoV-2 nucleocapsid protein.
Schuck PZhao H
mBio
2023 Dec 19

Diversity of Short Linear Interaction Motifs in SARS-CoV-2 Nucleocapsid Protein.
Schuck PZhao H
bioRxiv
2023 Aug 01

An automated interface for sedimentation velocity analysis in SEDFIT.
Schuck PTo SCZhao H
PLoS Comput Biol
2023 Sep

An automated interface for sedimentation velocity analysis in SEDFIT.
Schuck PTo SCZhao H
bioRxiv
2023 May 14

A conserved oligomerization domain in the disordered linker of coronavirus nucleocapsid proteins.
Zhao HWu DHassan SANguyen AChen JPiszczek GSchuck P
Sci Adv
2023 Apr 05

Crk proteins activate the Rap1 guanine nucleotide exchange factor C3G by segregated adaptor-dependent and -independent mechanisms.
Rodríguez-Blázquez ACarabias AMorán-Vaquero Ade Cima SLuque-Ortega JRAlfonso CSchuck PManso JAMacedo-Ribeiro SGuerrero Cde Pereda JM
Cell Commun Signal
2023 Feb 03

Plasticity in structure and assembly of SARS-CoV-2 nucleocapsid protein.
Zhao HNguyen AWu DLi YHassan SAChen JShroff HPiszczek GSchuck P
PNAS Nexus
2022 May

Plasticity in structure and assembly of SARS-CoV-2 nucleocapsid protein.
Zhao HNguyen AWu DLi YHassan SAChen JShroff HPiszczek GSchuck P
bioRxiv
2022 Feb 09

Best Practices for Aggregate Quantitation of Antibody Therapeutics by Sedimentation Velocity Analytical Ultracentrifugation.
Bou-Assaf GMBudyak ILBrenowitz MDay ESHayes DHill JMajumdar RRinghieri PSchuck PLin JC
J Pharm Sci
2022 Jul

The intrinsic kinase activity of BRD4 spans its BD2-B-BID domains.
Weissman JDSingh AKDevaiah BNSchuck PLaRue RCSinger DS
J Biol Chem
2021 Nov

Competing stress-dependent oligomerization pathways regulate self-assembly of the periplasmic protease-chaperone DegP.
Harkness RWToyama YRipstein ZAZhao HSever AIMLuan QBrady JPClark PLSchuck PKay LE
Proc Natl Acad Sci U S A
2021 Aug 10

A multi-step nucleation process determines the kinetics of prion-like domain phase separation.
Martin EWHarmon TSHopkins JBChakravarthy SIncicco JJSchuck PSoranno AMittag T
Nat Commun
2021 Jul 23

Characterization of DNA-protein complexes by nanoparticle tracking analysis and their association with systemic lupus erythematosus.
Juul-Madsen KTroldborg AWittenborn TRAxelsen MGZhao HKlausen LHLuecke SPaludan SRStengaard-Pedersen KDong MMøller HJThiel SJensen HSchuck PSutherland DSDegn SEVorup-Jensen T
Proc Natl Acad Sci U S A
2021 Jul 27

Biomolecular interactions of ultrasmall metallic nanoparticles and nanoclusters.
Sousa AASchuck PHassan SA
Nanoscale Adv
2021 Apr 28

Energetic and structural features of SARS-CoV-2 N-protein co-assemblies with nucleic acids.
Zhao HWu DNguyen ALi YAdão RCValkov EPatterson GHPiszczek GSchuck P
iScience
2021 Jun 25

A multi-laboratory benchmark study of isothermal titration calorimetry (ITC) using Ca and Mg binding to EDTA.
Velazquez-Campoy AClaro BAbian OHöring JBourlon LClaveria-Gimeno REnnifar EEngland PChaires JBWu DPiszczek GBrautigam CTso SCZhao HSchuck PKeller SBastos M
Eur Biophys J
2021 May

Determining the Stoichiometry of a Protein-Polymer Conjugate Using Multisignal Sedimentation Velocity Analytical Ultracentrifugation.
Clardy SMLee DHSchuck P
Bioconjug Chem
2021 May 19

Global multi-method analysis of interaction parameters for reversibly self-associating macromolecules at high concentrations.
Parupudi AChaturvedi SKAdão RHarkness RWDragulin-Otto SKay LEEsfandiary RZhao HSchuck P
Sci Rep
2021 Mar 11

Energetic and structural features of SARS-CoV-2 N-protein co-assemblies with nucleic acids.
Zhao HWu DNguyen ALi YAdão RCValkov EPatterson GHPiszczek GSchuck P
bioRxiv
2021 Feb 09

Calibrating analytical ultracentrifuges.
Zhao HNguyen ATo SCSchuck P
Eur Biophys J
2021 May

An intrinsically disordered motif regulates the interaction between the p47 adaptor and the p97 AAA+ ATPase.
Conicella AEHuang RRipstein ZANguyen AWang ELöhr TSchuck PVendruscolo MRubinstein JLKay LE
Proc Natl Acad Sci U S A
2020 Oct 20

Measuring aggregates, self-association, and weak interactions in concentrated therapeutic antibody solutions.
Chaturvedi SKParupudi AJuul-Madsen KNguyen AVorup-Jensen TDragulin-Otto SZhao HEsfandiary RSchuck P
MAbs
2020

Quantitative Analysis of Protein Self-Association by Sedimentation Velocity.
Zhao HLi WChu WBollard MAdão RSchuck P
Curr Protoc Protein Sci
2020 Sep

Ultrasmall Gold Nanoparticles Coated with Zwitterionic Glutathione Monoethyl Ester: A Model Platform for the Incorporation of Functional Peptides.
Knittel LLZhao HNguyen AMiranda ASchuck PSousa AA
J Phys Chem B
2020 May 14

The biofilm adhesion protein Aap from forms zinc-dependent amyloid fibers.
Yarawsky AEJohns SLSchuck PHerr AB
J Biol Chem
2020 Apr 03

Nucleic acid-induced dimerization of HIV-1 Gag protein.
Zhao HDatta SAKKim SHTo SCChaturvedi SKRein ASchuck P
J Biol Chem
2019 Nov 08

Efficient data acquisition with three-channel centerpieces in sedimentation velocity.
Juul-Madsen KZhao HVorup-Jensen TSchuck P
Anal Biochem
2019 Dec 01

All tubulins are not alike: Heterodimer dissociation differs among different biological sources.
Montecinos-Franjola FChaturvedi SKSchuck PSackett DL
J Biol Chem
2019 Jun 28

Enhanced Sample Handling for Analytical Ultracentrifugation with 3D-Printed Centerpieces.
To SCBrautigam CAChaturvedi SKBollard MTKrynitsky JKakareka JWPohida TJZhao HSchuck P
Anal Chem
2019 May 07

Allosteric inhibition of α-thrombin enzymatic activity with ultrasmall gold nanoparticles.
Lira ALFerreira RSTorquato RJSOliva MLVSchuck PSousa AA
Nanoscale Adv
2019 Jan 01

A formally exact one-frequency-only Bethe-Salpeter-like equation. Similarities and differences between GW+BSE and self-consistent RPA.
Olevano VToulouse JSchuck P
J Chem Phys
2019 Feb 28

A Reappraisal of Sedimentation Nonideality Coefficients for the Analysis of Weak Interactions of Therapeutic Proteins.
Chaturvedi SKSchuck P
AAPS J
2019 Feb 27

Measuring Ultra-Weak Protein Self-Association by Non-ideal Sedimentation Velocity.
Chaturvedi SKSagar VZhao HWistow GSchuck P
J Am Chem Soc
2019 Feb 20

Cooperative assembly of a four-molecule signaling complex formed upon T cell antigen receptor activation.
Manna AZhao HWada JBalagopalan LTagad HDAppella ESchuck PSamelson LE
Proc Natl Acad Sci U S A
2018 Dec 18

Role of humoral immunity against hepatitis B virus core antigen in the pathogenesis of acute liver failure.
Chen ZDiaz GPollicino TZhao HEngle RESchuck PShen CHZamboni FLong ZKabat JDe Battista DBock KWMoore INWollenberg KSoto CGovindarajan SKwong PDKleiner DEPurcell RHFarci P
Proc Natl Acad Sci U S A
2018 Nov 27

Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5.
Ge JElferich JGoehring AZhao HSchuck PGouaux E
Elife
2018 Aug 02

A radial calibration window for analytical ultracentrifugation.
LeBrun TSchuck PWei RYoon JSDong XMorgan NYFagan JZhao H
PLoS One
2018

Congratulations to Dr. Fumio Arisaka on his 70th birthday.
Schuck P
Biophys Rev
2018 Apr

Binding kinetics of ultrasmall gold nanoparticles with proteins.
Lira ALFerreira RSTorquato RJSZhao HOliva MLVHassan SASchuck PSousa AA
Nanoscale
2018 Feb 15

Preferential assembly of heteromeric kainate and AMPA receptor amino terminal domains.
Zhao HLomash SChittori SGlasser CMayer MLSchuck P
Elife
2017 Oct 23

Use of fluorescence-detected sedimentation velocity to study high-affinity protein interactions.
Chaturvedi SKMa JZhao HSchuck P
Nat Protoc
2017 Sep

Crystal Structure of Chicken γS-Crystallin Reveals Lattice Contacts with Implications for Function in the Lens and the Evolution of the βγ-Crystallins.
Sagar VChaturvedi SKSchuck PWistow G
Structure
2017 Jul 05

An allosteric site in the T-cell receptor Cβ domain plays a critical signalling role.
Natarajan KMcShan ACJiang JKumirov VKWang RZhao HSchuck PTilahun MEBoyd LFYing JBax AMargulies DHSgourakis NG
Nat Commun
2017 May 16

Sedimentation of Reversibly Interacting Macromolecules with Changes in Fluorescence Quantum Yield.
Chaturvedi SKZhao HSchuck P
Biophys J
2017 Apr 11

Measuring Protein Interactions by Optical Biosensors.
Zhao HBoyd LFSchuck P
Curr Protoc Protein Sci
2017 Apr 03

3D-Printing for Analytical Ultracentrifugation.
Desai AKrynitsky JPohida TJZhao HSchuck P
PLoS One
2016

Monochromatic multicomponent fluorescence sedimentation velocity for the study of high-affinity protein interactions.
Zhao HFu YGlasser CAndrade Alba EJMayer MLPatterson GSchuck P
Elife
2016 Jul 20

Higher-order oligomerization promotes localization of SPOP to liquid nuclear speckles.
Marzahn MRMarada SLee JNourse AKenrick SZhao HBen-Nissan GKolaitis RMPeters JLPounds SErrington WJPrivé GGTaylor JPSharon MSchuck POgden SKMittag T
EMBO J
2016 Jun 15

Sedimentation coefficient distributions of large particles.
Schuck P
Analyst
2016 Jul 21

Integration and global analysis of isothermal titration calorimetry data for studying macromolecular interactions.
Brautigam CAZhao HVargas CKeller SSchuck P
Nat Protoc
2016 May

Biointeractions of ultrasmall glutathione-coated gold nanoparticles: effect of small size variations.
Sousa AAHassan SAKnittel LLBalbo AAronova MABrown PHSchuck PLeapman RD
Nanoscale
2016 Mar 28

Tubulin Dimer Reversible Dissociation: AFFINITY, KINETICS, AND DEMONSTRATION OF A STABLE MONOMER.
Montecinos-Franjola FSchuck PSackett DL
J Biol Chem
2016 Apr 22

Interaction of TAPBPR, a tapasin homolog, with MHC-I molecules promotes peptide editing.
Morozov GIZhao HMage MGBoyd LFJiang JDolan MAVenna RNorcross MAMcMurtrey CPHildebrand WSchuck PNatarajan KMargulies DH
Proc Natl Acad Sci U S A
2016 Feb 23

Variable Field Analytical Ultracentrifugation: II. Gravitational Sweep Sedimentation Velocity.
Ma JZhao HSandmaier JAlexander Liddle JSchuck P
Biophys J
2016 Jan 05

AUC and Small-Angle Scattering for Membrane Proteins.
Le Roy AWang KSchaack BSchuck PBreyton CEbel C
Methods Enzymol
2015

Variable-Field Analytical Ultracentrifugation: I. Time-Optimized Sedimentation Equilibrium.
Ma JMetrick MGhirlando RZhao HSchuck P
Biophys J
2015 Aug 18

A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation.
Zhao HGhirlando RAlfonso CArisaka FAttali IBain DLBakhtina MMBecker DFBedwell GJBekdemir ABesong TMBirck CBrautigam CABrennerman WByron OBzowska AChaires JBChaton CTCölfen HConnaghan KDCrowley KACurth UDaviter TDean WLDíez AIEbel CEckert DMEisele LEEisenstein EEngland PEscalante CFagan JAFairman RFinn RMFischle Wde la Torre JGGor JGustafsson HHall DHarding SECifre JGHerr ABHowell EEIsaac RSJao SCJose DKim SJKokona BKornblatt JAKosek DKrayukhina EKrzizike DKusznir EAKwon HLarson ALaue TMLe Roy ALeech APLilie HLuger KLuque-Ortega JRMa JMay CAMaynard ELModrak-Wojcik AMok YFMücke NNagel-Steger LNarlikar GJNoda MNourse AObsil TPark CKPark JKPawelek PDPerdue EEPerkins SJPerugini MAPeterson CLPeverelli MGPiszczek GPrag GPrevelige PERaynal BDRezabkova LRichter KRingel AERosenberg RRowe AJRufer ACScott DJSeravalli JGSolovyova ASSong RStaunton DStoddard CStott KStrauss HMStreicher WWSumida JPSwygert SGSzczepanowski RHTessmer IToth RTTripathy AUchiyama SUebel SFUnzai SGruber AVvon Hippel PHWandrey CWang SHWeitzel SEWielgus-Kutrowska BWolberger CWolff MWright EWu YSWubben JMSchuck P
PLoS One
2015

A histogram approach to the quality of fit in sedimentation velocity analyses.
Ma JZhao HSchuck P
Anal Biochem
2015 Aug 15

Biocalorimetry.
Chaires JBHansen LDKeller SBrautigam CAZhao HSchuck P
Methods
2015 Apr

Combining biophysical methods for the analysis of protein complex stoichiometry and affinity in SEDPHAT.
Zhao HSchuck P
Acta Crystallogr D Biol Crystallogr
2015 Jan 01

SEDPHAT--a platform for global ITC analysis and global multi-method analysis of molecular interactions.
Zhao HPiszczek GSchuck P
Methods
2015 Apr

Accounting for photophysical processes and specific signal intensity changes in fluorescence-detected sedimentation velocity.
Zhao HMa JIngaramo MAndrade EMacDonald JRamsay GPiszczek GPatterson GHSchuck P
Anal Chem
2014 Sep 16

Measurement of the temperature of the resting rotor in analytical ultracentrifugation.
Ghirlando RZhao HBalbo APiszczek GCurth UBrautigam CASchuck P
Anal Biochem
2014 Aug 01

A structural framework for a near-minimal form of life: mass and compositional analysis of the helical mollicute Spiroplasma melliferum BC3.
Trachtenberg SSchuck PPhillips TMAndrews SBLeapman RD
PLoS One
2014

Analysis of protein interactions with picomolar binding affinity by fluorescence-detected sedimentation velocity.
Zhao HMayer MLSchuck P
Anal Chem
2014 Mar 18

Improved measurement of the rotor temperature in analytical ultracentrifugation.
Zhao HBalbo AMetger HClary RGhirlando RSchuck P
Anal Biochem
2014 Apr 15

Human herpesvirus 7 U21 tetramerizes to associate with class I major histocompatibility complex molecules.
May NAWang QBalbo AKonrad SLBuchli RHildebrand WHSchuck PHudson AW
J Virol
2014 Mar

Solution properties of γ-crystallins: hydration of fish and mammal γ-crystallins.
Zhao HChen YRezabkova LWu ZWistow GSchuck P
Protein Sci
2014 Jan

SEDFIT-MSTAR: molecular weight and molecular weight distribution analysis of polymers by sedimentation equilibrium in the ultracentrifuge.
Schuck PGillis RBBesong TMAlmutairi FAdams GGRowe AJHarding SE
Analyst
2014 Jan 07

Solution properties of γ-crystallins: compact structure and low frictional ratio are conserved properties of diverse γ-crystallins.
Chen YZhao HSchuck PWistow G
Protein Sci
2014 Jan

Analysis of high affinity self-association by fluorescence optical sedimentation velocity analytical ultracentrifugation of labeled proteins: opportunities and limitations.
Zhao HLomash SGlasser CMayer MLSchuck P
PLoS One
2013

Complexes of neutralizing and non-neutralizing affinity matured Fabs with a mimetic of the internal trimeric coiled-coil of HIV-1 gp41.
Gustchina ELi MGhirlando RSchuck PLouis JMPierson JRao PSubramaniam SGustchina AClore GMWlodawer A
PLoS One
2013

Tools for the quantitative analysis of sedimentation boundaries detected by fluorescence optical analytical ultracentrifugation.
Zhao HCasillas EShroff HPatterson GHSchuck P
PLoS One
2013

Multipoint binding of the SLP-76 SH2 domain to ADAP is critical for oligomerization of SLP-76 signaling complexes in stimulated T cells.
Coussens NPHayashi RBrown PHBalagopalan LBalbo AAkpan IHoutman JCBarr VASchuck PAppella ESamelson LE
Mol Cell Biol
2013 Nov

Analysis of high-affinity assembly for AMPA receptor amino-terminal domains.
Zhao HBerger AJBrown PHKumar JBalbo AMay CACasillas ELaue TMPatterson GHMayer MLSchuck P
J Gen Physiol
2013 Jun

Improving the thermal, radial, and temporal accuracy of the analytical ultracentrifuge through external references.
Ghirlando RBalbo APiszczek GBrown PHLewis MSBrautigam CASchuck PZhao H
Anal Biochem
2013 Sep 01

Multi-signal sedimentation velocity analysis with mass conservation for determining the stoichiometry of protein complexes.
Brautigam CAPadrick SBSchuck P
PLoS One
2013

Analytical Ultracentrifugation as a Tool for Studying Protein Interactions.
Schuck P
Biophys Rev
2013 Jun 01

Biophysical methods for the study of protein interactions.
Schuck PZhao H
Methods
2013 Mar

A conformational switch in HP1 releases auto-inhibition to drive heterochromatin assembly.
Canzio DLiao MNaber NPate ELarson AWu SMarina DBGarcia JFMadhani HDCooke RSchuck PCheng YNarlikar GJ
Nature
2013 Apr 18

Recorded scan times can limit the accuracy of sedimentation coefficients in analytical ultracentrifugation.
Zhao HGhirlando RPiszczek GCurth UBrautigam CASchuck P
Anal Biochem
2013 Jun 01

Overview of current methods in sedimentation velocity and sedimentation equilibrium analytical ultracentrifugation.
Zhao HBrautigam CAGhirlando RSchuck P
Curr Protoc Protein Sci
2013 Feb

A comparison of binding surfaces for SPR biosensing using an antibody-antigen system and affinity distribution analysis.
Zhao HGorshkova IIFu GLSchuck P
Methods
2013 Mar

Density contrast sedimentation velocity for the determination of protein partial-specific volumes.
Brown PHBalbo AZhao HEbel CSchuck P
PLoS One
2011

NBD-labeled phospholipid accelerates apolipoprotein C-II amyloid fibril formation but is not incorporated into mature fibrils.
Ryan TMGriffin MDBailey MFSchuck PHowlett GJ
Biochemistry
2011 Nov 08

Malaria vaccine candidate: design of a multivalent subunit α-helical coiled coil poly-epitope.
Olugbile SVillard VBertholet SJafarshad AKulangara CRoussilhon CFrank GAgak GWFelger INebie IKonate KKajava AVSchuck PDruilhe PSpertini FCorradin G
Vaccine
2011 Sep 16

Structure and assembly mechanism for heteromeric kainate receptors.
Kumar JSchuck PMayer ML
Neuron
2011 Jul 28

The molecular refractive function of lens γ-Crystallins.
Zhao HBrown PHMagone MTSchuck P
J Mol Biol
2011 Aug 19

The role of macromolecular crowding in the evolution of lens crystallins with high molecular refractive index.
Zhao HMagone MTSchuck P
Phys Biol
2011 Aug

On the distribution of protein refractive index increments.
Zhao HBrown PHSchuck P
Biophys J
2011 May 04

Editorial for the special issue of methods "Modern Analytical Ultracentrifugation".
Schuck PZhao H
Methods
2011 May

Dimeric states of neural- and epithelial-cadherins are distinguished by the rate of disassembly.
Vunnam NFlint JBalbo ASchuck PPedigo S
Biochemistry
2011 Apr 12

The boundary structure in the analysis of reversibly interacting systems by sedimentation velocity.
Zhao HBalbo ABrown PHSchuck P
Methods
2011 May

Extended Fujita approach to the molecular weight distribution of polysaccharides and other polymeric systems.
Harding SESchuck PAbdelhameed ASAdams GKök MSMorris GA
Methods
2011 May

Biophysical characterization of DNA and RNA aptamer interactions with hen egg lysozyme.
Potty ASKourentzi KFang HSchuck PWillson RC
Int J Biol Macromol
2011 Apr 01

Assembly, loading, and alignment of an analytical ultracentrifuge sample cell.
Balbo AZhao HBrown PHSchuck P
J Vis Exp
2009 Nov 05

On the analysis of sedimentation velocity in the study of protein complexes.
Brown PHBalbo ASchuck P
Eur Biophys J
2009 Oct

Energetics of glutamate receptor ligand binding domain dimer assembly are modulated by allosteric ions.
Chaudhry CPlested AJSchuck PMayer ML
Proc Natl Acad Sci U S A
2009 Jul 28

Novel chimpanzee/human monoclonal antibodies that neutralize anthrax lethal factor, and evidence for possible synergy with anti-protective antigen antibody.
Chen ZMoayeri MCrown DEmerson SGorshkova ISchuck PLeppla SHPurcell RH
Infect Immun
2009 Sep

The N-terminal domain of GluR6-subtype glutamate receptor ion channels.
Kumar JSchuck PJin RMayer ML
Nat Struct Mol Biol
2009 Jun

The C-terminal domain of Plasmodium falciparum merozoite surface protein 3 self-assembles into alpha-helical coiled coil tetramer.
Gondeau CCorradin GHeitz FLe Peuch CBalbo ASchuck PKajava AV
Mol Biochem Parasitol
2009 Jun

Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization.
Chaudhry CWeston MCSchuck PRosenmund CMayer ML
EMBO J
2009 May 20

Autoinhibition of Arf GTPase-activating protein activity by the BAR domain in ASAP1.
Jian XBrown PSchuck PGruschus JMBalbo AHinshaw JERandazzo PA
J Biol Chem
2009 Jan 16

Bayesian analysis of heterogeneity in the distribution of binding properties of immobilized surface sites.
Gorshkova IISvitel JRazjouyan FSchuck P
Langmuir
2008 Oct 21

A bayesian approach for quantifying trace amounts of antibody aggregates by sedimentation velocity analytical ultracentrifugation.
Brown PHBalbo ASchuck P
AAPS J
2008 Sep

Characterizing protein-protein interactions by sedimentation velocity analytical ultracentrifugation.
Brown PHBalbo ASchuck P
Curr Protoc Immunol
2008 May

Humanized monoclonal antibodies derived from chimpanzee Fabs protect against Japanese encephalitis virus in vitro and in vivo.
Goncalvez APChien CHTubthong KGorshkova IRoll CDonau OSchuck PYoksan SWang SDPurcell RHLai CJ
J Virol
2008 Jul

Apolipoprotein C-II amyloid fibrils assemble via a reversible pathway that includes fibril breaking and rejoining.
Binger KJPham CLWilson LMBailey MFLawrence LJSchuck PHowlett GJ
J Mol Biol
2008 Feb 29

A new adaptive grid-size algorithm for the simulation of sedimentation velocity profiles in analytical ultracentrifugation.
Brown PHSchuck P
Comput Phys Commun
2008 Jan 15

Bacteriorhodopsin/amphipol complexes: structural and functional properties.
Gohon YDahmane TRuigrok RWSchuck PCharvolin DRappaport FTimmins PEngelman DMTribet CPopot JLEbel C
Biophys J
2008 May 01

Extended polypeptide linkers establish the spatial architecture of a pyruvate dehydrogenase multienzyme complex.
Lengyel JSStott KMWu XBrooks BRBalbo ASchuck PPerham RNSubramaniam SMilne JL
Structure
2008 Jan

Measuring protein-protein interactions by equilibrium sedimentation.
Balbo ABrown PHBraswell EHSchuck P
Curr Protoc Immunol
2007 Nov

Two interferons alpha influence each other during their interaction with the extracellular domain of human type interferon receptor subunit 2.
Schmeisser HGorshkova IBrown PHKontsek PSchuck PZoon KC
Biochemistry
2007 Dec 18

Cellular expression and crystal structure of the murine cytomegalovirus major histocompatibility complex class I-like glycoprotein, m153.
Mans JNatarajan KBalbo ASchuck PEikel DHess SRobinson HSimic HJonjic STiemessen CTMargulies DH
J Biol Chem
2007 Nov 30

Characterization of chimpanzee/human monoclonal antibodies to vaccinia virus A33 glycoprotein and its variola virus homolog in vitro and in a vaccinia virus mouse protection model.
Chen ZEarl PAmerico JDamon ISmith SKYu FSebrell AEmerson SCohen GEisenberg RJGorshkova ISchuck PSatterfield WMoss BPurcell R
J Virol
2007 Sep

Using prior knowledge in the determination of macromolecular size-distributions by analytical ultracentrifugation.
Brown PHBalbo ASchuck P
Biomacromolecules
2007 Jun

Single-walled tubulin ring polymers.
Boukari HSackett DLSchuck PNossal RJ
Biopolymers
2007

Superantigen natural affinity maturation revealed by the crystal structure of staphylococcal enterotoxin G and its binding to T-cell receptor Vbeta8.2.
Fernández MMBhattacharya SDe Marzi MCBrown PHKerzic MSchuck PMariuzza RAMalchiodi EL
Proteins
2007 Jul 01

Studying multisite binary and ternary protein interactions by global analysis of isothermal titration calorimetry data in SEDPHAT: application to adaptor protein complexes in cell signaling.
Houtman JCBrown PHBowden BYamaguchi HAppella ESamelson LESchuck P
Protein Sci
2007 Jan

Probing the functional heterogeneity of surface binding sites by analysis of experimental binding traces and the effect of mass transport limitation.
Svitel JBoukari HVan Ryk DWillson RCSchuck P
Biophys J
2007 Mar 01

Measuring protein interactions by optical biosensors.
Schuck PBoyd LFAndersen PS
Curr Protoc Cell Biol
2004 May

Case histories illustrating the utility of sertindole in clinical practice.
Schuck Pvan den Ameele HJaanson PRyckmans VHawley C
CNS Drugs
2004

SDR grafting of a murine antibody using multiple human germline templates to minimize its immunogenicity.
Gonzales NRPadlan EADe Pascalis RSchuck PSchlom JKashmiri SV
Mol Immunol
2004 Jul

Crystal structure of the C-terminal peptidoglycan-binding domain of human peptidoglycan recognition protein Ialpha.
Guan RMalchiodi ELWang QSchuck PMariuzza RA
J Biol Chem
2004 Jul 23

Assessing reproducibility for interval data in health-related quality of life questionnaires: which coefficient should be used?
Schuck P
Qual Life Res
2004 Apr

Calculating sedimentation coefficient distributions by direct modeling of sedimentation velocity concentration profiles.
Dam JSchuck P
Methods Enzymol
2004

Binding specificity of multiprotein signaling complexes is determined by both cooperative interactions and affinity preferences.
Houtman JCHigashimoto YDimasi NCho SYamaguchi HBowden BRegan CMalchiodi ELMariuzza RSchuck PAppella ESamelson LE
Biochemistry
2004 Apr 13

A model for sedimentation in inhomogeneous media. II. Compressibility of aqueous and organic solvents.
Schuck P
Biophys Chem
2004 Mar 01

A model for sedimentation in inhomogeneous media. I. Dynamic density gradients from sedimenting co-solutes.
Schuck P
Biophys Chem
2004 Mar 01

Sedimentation equilibrium analysis of protein interactions with global implicit mass conservation constraints and systematic noise decomposition.
Vistica JDam JBalbo AYikilmaz EMariuzza RARouault TASchuck P
Anal Biochem
2004 Mar 15

Conformational restriction blocks glutamate receptor desensitization.
Weston MCSchuck PGhosal ARosenmund CMayer ML
Nat Struct Mol Biol
2006 Dec

Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1.
Houtman JCYamaguchi HBarda-Saad MBraiman ABowden BAppella ESchuck PSamelson LE
Nat Struct Mol Biol
2006 Sep

Variable dimerization of the Ly49A natural killer cell receptor results in differential engagement of its MHC class I ligand.
Dam JBaber JGrishaev AMalchiodi ELSchuck PBax AMariuzza RA
J Mol Biol
2006 Sep 08

Macromolecular size-and-shape distributions by sedimentation velocity analytical ultracentrifugation.
Brown PHSchuck P
Biophys J
2006 Jun 15

Quaternary structure and cleavage specificity of a poxvirus holliday junction resolvase.
Garcia ADOtero JLebowitz JSchuck PMoss B
J Biol Chem
2006 Apr 28

Crystal structure of group A streptococcus Mac-1: insight into dimer-mediated specificity for recognition of human IgG.
Agniswamy JNagiec MJLiu MSchuck PMusser JMSun PD
Structure
2006 Feb

Efficient neutralization of anthrax toxin by chimpanzee monoclonal antibodies against protective antigen.
Chen ZMoayeri MZhou YHLeppla SEmerson SSebrell AYu FSvitel JSchuck PSt Claire MPurcell R
J Infect Dis
2006 Mar 01

Chimpanzee/human mAbs to vaccinia virus B5 protein neutralize vaccinia and smallpox viruses and protect mice against vaccinia virus.
Chen ZEarl PAmerico JDamon ISmith SKZhou YHYu FSebrell AEmerson SCohen GEisenberg RJSvitel JSchuck PSatterfield WMoss BPurcell R
Proc Natl Acad Sci U S A
2006 Feb 07

Influence of temperature on the conformation of canine plasminogen: an analytical ultracentrifugation and dynamic light scattering study.
Kornblatt JASchuck P
Biochemistry
2005 Oct 04

Dissection of merozoite surface protein 3, a representative of a family of Plasmodium falciparum surface proteins, reveals an oligomeric and highly elongated molecule.
Burgess BRSchuck PGarboczi DN
J Biol Chem
2005 Nov 04

Regulation of ASAP1 by phospholipids is dependent on the interface between the PH and Arf GAP domains.
Che MMBoja ESYoon HYGruschus JJaffe HStauffer SSchuck PFales HMRandazzo PA
Cell Signal
2005 Oct

Self-association and ligand-induced conformational changes of iron regulatory proteins 1 and 2.
Yikilmaz ERouault TASchuck P
Biochemistry
2005 Jun 14

A mechanism for assembly of complexes of vitronectin and plasminogen activator inhibitor-1 from sedimentation velocity analysis.
Minor KHSchar CRBlouse GEShore JDLawrence DASchuck PPeterson CB
J Biol Chem
2005 Aug 05

Sedimentation velocity analysis of heterogeneous protein-protein interactions: Lamm equation modeling and sedimentation coefficient distributions c(s).
Dam JVelikovsky CAMariuzza RAUrbanke CSchuck P
Biophys J
2005 Jul

Sedimentation velocity analysis of heterogeneous protein-protein interactions: sedimentation coefficient distributions c(s) and asymptotic boundary profiles from Gilbert-Jenkins theory.
Dam JSchuck P
Biophys J
2005 Jul

Eukaryotic RNases H1 act processively by interactions through the duplex RNA-binding domain.
Gaidamakov SAGorshkova IISchuck PSteinbach PJYamada HCrouch RJCerritelli SM
Nucleic Acids Res
2005

Characterization of DC-SIGN/R interaction with human immunodeficiency virus type 1 gp120 and ICAM molecules favors the receptor's role as an antigen-capturing rather than an adhesion receptor.
Snyder GAFord JTorabi-Parizi PArthos JASchuck PColonna MSun PD
J Virol
2005 Apr

Cooperative behavior of Escherichia coli cell-division protein FtsZ assembly involves the preferential cyclization of long single-stranded fibrils.
González JMVélez MJiménez MAlfonso CSchuck PMingorance JVicente MMinton APRivas G
Proc Natl Acad Sci U S A
2005 Feb 08

Targeted lysis of HIV-infected cells by natural killer cells armed and triggered by a recombinant immunoglobulin fusion protein: implications for immunotherapy.
Gupta NArthos JKhazanie PSteenbeke TDCensoplano NMChung EACruz CCChaikin MADaucher MKottilil SMavilio DSchuck PSun PDRabin RLRadaev SVan Ryk DCicala CFauci AS
Virology
2005 Feb 20

Exposure of acidic residues as a danger signal for recognition of fibrinogen and other macromolecules by integrin alphaXbeta2.
Vorup-Jensen TCarman CVShimaoka MSchuck PSvitel JSpringer TA
Proc Natl Acad Sci U S A
2005 Feb 01

Studying multiprotein complexes by multisignal sedimentation velocity analytical ultracentrifugation.
Balbo AMinor KHVelikovsky CAMariuzza RAPeterson CBSchuck P
Proc Natl Acad Sci U S A
2005 Jan 04

In vitro affinity maturation of a specificity-determining region-grafted humanized anticarcinoma antibody: isolation and characterization of minimally immunogenic high-affinity variants.
De Pascalis RGonzales NRPadlan EASchuck PBatra SKSchlom JKashmiri SV
Clin Cancer Res
2003 Nov 15

Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b).
Dam JGuan RNatarajan KDimasi NChlewicki LKKranz DMSchuck PMargulies DHMariuzza RA
Nat Immunol
2003 Dec

Minimizing immunogenicity of the SDR-grafted humanized antibody CC49 by genetic manipulation of the framework residues.
Gonzales NRPadlan EADe Pascalis RSchuck PSchlom JKashmiri SV
Mol Immunol
2003 Oct

Reversible and fast association equilibria of a molecular chaperone, gp57A, of bacteriophage T4.
Ali SAIwabuchi NMatsui THirota KKidokoro SArai MKuwajima KSchuck PArisaka F
Biophys J
2003 Oct

On the analysis of protein self-association by sedimentation velocity analytical ultracentrifugation.
Schuck P
Anal Biochem
2003 Sep 01

The 'smallest real difference' as a measure of sensitivity to change: a critical analysis.
Schuck PZwingmann C
Int J Rehabil Res
2003 Jun

Alanine-scanning mutations in domain 4 of anthrax toxin protective antigen reveal residues important for binding to the cellular receptor and to a neutralizing monoclonal antibody.
Rosovitz MJSchuck PVarughese MChopra APMehra VSingh YMcGinnis LMLeppla SH
J Biol Chem
2003 Aug 15

Combined affinity and rate constant distributions of ligand populations from experimental surface binding kinetics and equilibria.
Svitel JBalbo AMariuzza RAGonzales NRSchuck P
Biophys J
2003 Jun

Inhibition of hemostasis by a high affinity biogenic amine-binding protein from the saliva of a blood-feeding insect.
Andersen JFFrancischetti IMValenzuela JGSchuck PRibeiro JM
J Biol Chem
2003 Feb 14

Differences in the binding capacity of human apolipoprotein E3 and E4 to size-fractionated lipid emulsions.
Perugini MASchuck PHowlett GJ
Eur J Biochem
2002 Dec

Grafting of "abbreviated" complementarity-determining regions containing specificity-determining residues essential for ligand contact to engineer a less immunogenic humanized monoclonal antibody.
De Pascalis RIwahashi MTamura MPadlan EAGonzales NRSantos ADGiuliano MSchuck PSchlom JKashmiri SV
J Immunol
2002 Sep 15

Surface plasmon resonance-based competition assay to assess the sera reactivity of variants of humanized antibodies.
Gonzales NRSchuck PSchlom JKashmiri SV
J Immunol Methods
2002 Oct 15

Modern analytical ultracentrifugation in protein science: a tutorial review.
Lebowitz JLewis MSSchuck P
Protein Sci
2002 Sep

Epidemiology research.
Schuck P
Lancet
2002 Jul 20

Analysis of a temperature-sensitive mutant rotavirus indicates that NSP2 octamers are the functional form of the protein.
Taraporewala ZFSchuck PRamig RFSilvestri LPatton JT
J Virol
2002 Jul

Mass spectrometry after capture and small-volume elution of analyte from a surface plasmon resonance biosensor.
Gilligan JJSchuck PYergey AL
Anal Chem
2002 May 01

Quantifying the energetics of cooperativity in a ternary protein complex.
Andersen PSSchuck PSundberg EJGeisler CKarjalainen KMariuzza RA
Biochemistry
2002 Apr 23

Size-distribution analysis of proteins by analytical ultracentrifugation: strategies and application to model systems.
Schuck PPerugini MAGonzales NRHowlett GJSchubert D
Biophys J
2002 Feb

Biochemical and biological characterization of a dodecameric CD4-Ig fusion protein: implications for therapeutic and vaccine strategies.
Arthos JCicala CSteenbeke TDChun TWDela Cruz CHanback DBKhazanie PNam DSchuck PSelig SMVan Ryk DChaikin MAFauci AS
J Biol Chem
2002 Mar 29

Elucidating kinetic and thermodynamic constants for interaction of G protein subunits and receptors by surface plasmon resonance spectroscopy.
Rebois RVSchuck PNorthup JK
Methods Enzymol
2002