NEWS & EVENTS
What is the Alzheimer's Disease Neuroimaging Initiative (ADNI?)
Dr. Paul Thompson discusses the Alzheimer's Disease Neuroimaging Initiative (ADNI), an imaging project that attempts to discover the best predictors and measures of Alzheimer's Disease. The hope is that a treatment or cure could be developed by better understanding what happens to the brain when it is diseased. He also discusses non-medical interventions that have been shown to help protect against Alzheimer's. For more information visit: http://www.loni.ucla.edu/ http://www.humanconnectomeproject.org/ Photos courtesy of: LONI, the Human Connectome Project
DEBUT Winner: FastStitch
QuickStitch: Surgical Suturing Device to Improve Fascia Closure QuickStitch was the winner in the category of Therapeutic Devices. The winning team from Johns Hopkins University was comprised of Anvesh Annadanam, Luis Herrera, Daniel Peng, Ang Tu, and Sohail Zahid. FastStitch is an inexpensive, disposable suturing tool for gastrointestinal surgery that improves safety, efficiency, and consistency in stitching fascia (a collagenous layer underneath the skin that wraps around the internal organs to keep them from pressing against the skin layer). The device aims to improve surgeon performance and patient outcomes by regulating stitch placement and tension, thus helping to avoid the problems of hernias and ischemia that can result from improper stitching after gastrointestinal surgery. For more information on Debut visit: http://www.nibib.nih.gov/Training/Und...
Teaming Up: Imaging and Genetics
Dr. Paul Thompson discusses the possibilities of combining the latest brain imaging technology with the study of genetics. For more information visit: http://www.loni.ucla.edu/ http://www.humanconnectomeproject.org/ Photos courtesy of: LONI, the Human Connectome Project
DEBUT Winner: QPath
QPath: A Flow-Through High-Throughput Quantitative Histology Platform In the category of Diagnostic Devices the winning project was Q-Path, submitted by Armin Arshi, David Kuo, Robert Lee, Elizabeth Ng, and Andrew Tan from the University of California Los Angeles. The project addressed the most common form of bladder cancer, transitional cell carcinoma (TCC), which is the fourth most common and ninth most deadly form of cancer in men. The team developed a high-throughput, flow-through microfluidic platform combined with automated image analysis software, which allows for systematic screening of patients' urine samples in order to noninvasively diagnose TCC. The system provides the pathologist with a quantitative analysis of the sample and an index to differentiate between healthy, low-grade malignancy, and high-grade malignancy. The device has the potential to be applied to a broader range of bodily fluid samples, including blood and pleural fluids; hence it could play a key role in the early diagnosis of various types of cancers. For more information on DEBUT visit: http://www.nibib.nih.gov/Training/Und...
Exercise, Stress, and the Brain
Dr. Paul Thompson talks about how imaging has revealed the positive effects of exercise on the brain as well as the detrimental effects of stress and cortisol on the brain. For more information visit: http://www.loni.ucla.edu/ http://www.humanconnectomeproject.org/ Photos courtesy of: LONI, the Human Connectome Project
DEBUT Winner: Low-Cost Spirometer
Low-Cost Spirometer In the category of Technology to Aid Underserved Populations and Individuals with Disabilities the winning project, Low-Cost Spirometer, addressed the lack of devices to measure lung function for the diagnosis and monitoring of respiratory diseases in the developing world. Andrew Brimer, Abigail Cohen, Braden Eliason, Olga Neyman, and Charles Wu from Washington University in St. Louis designed a fluidic oscillating spirometer that costs under $10. The device offers a significant cost reduction compared with traditional spirometers costing $1,000-$2,000, without compromising accuracy or precision. With respiratory diseases like COPD on the rise, the durable low-cost spirometer could improve healthcare in the developing as well as the developed world. For more information on DEBUT visit: www.nibib.nih.gov/Training/UndergradGrad/debut
Picturing the Brain
Dr. Paul Thompson talks about the work that he does at the Lab of Neuro Imaging (LONI) at UCLA. He discusses brain health, the latest brain imaging technology and projects like ENIGMA, which involves a world-wide effort to create a brain database. For more information visit: http://www.loni.ucla.edu/ http://www.humanconnectomeproject.org/ Photos courtesy of: LONI lab, the Human Connectome Project, and iStock
Dr. Carla Pugh: Use of Sensors and Simulation Technology to Quantify Clinical Palpation
NIBIB grantee Dr. Carla Pugh discussed the need for practical, tangible educational tools for doctors and surgeons that can give quantifiable information on the effectiveness of the exam or procedure being performed. Some of the tools she developed to help doctors learn to diagnose breast tumors were on display at the technology showcase.