Creating Biomedical Technologies to Improve Health

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Science Highlights • February 29, 2012
Prostate cancer is the most common cancer and the second leading cause of cancer-related death in men. Successful treatment of prostate cancer relies in part on its early and accurate detection. Conventional prostate imaging approaches including ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) are not sensitive enough to detect very small tumors in the prostate or signs that the disease has metastasized (spread). A new class of agents known as viral nanoparticles offers the opportunity to improve detection of small lumps of cancer cells.
Grantee News • February 3, 2012
One of the fastest growing clinical applications of the powerful medical imaging modality MRI is the parallel imaging method, where multiple radio frequency (RF) receiver coils are used in simultaneous signal processing to speed up imaging.
Grantee News • January 26, 2012
NIBIB researcher Claude Lechene and colleagues report the first use of an approach called multi-isotope imaging spectrometry (MMIS) in living organisms. This technique has outstanding resolution: it provides data in the sub-micrometre range, allowing analysis of structures as small as cellular regions. Read the full article from Nature.
Science Highlights • January 15, 2012
New drugs are always tested in animals before they are tried in people. However, due to differences in the way that animals and people process drugs in the liver, animal models cannot predict dangerous drug side effects that are unique to humans. To tackle this problem, researchers at the Massachusetts Institute of Technology (MIT) engineered a new mouse model that harbors a tiny human liver. The mouse can be used to study drug safety and efficacy, drug-drug interactions, and human diseases such as hepatitis C.
Press Releases • January 11, 2012
Three new members have been appointed to the National Advisory Council for Biomedical Imaging and Bioengineering (NACBIB) of the National Institute of Biomedical Imaging and Bioengineering (NIBIB).
Science Highlights • December 30, 2011
As the world population ages, the number of people affected with Alzheimer’s disease is rising steadily. While there is yet no cure, certain drugs can slow Alzheimer’s progression, particularly if started early. University of Utah researchers are developing new brain imaging tools that may help doctors diagnose Alzheimer’s much earlier and more accurately than is possible with currently available tests.
Grantee News • December 19, 2011
NITRC currently gives researchers around the world access to software tools and data to advance neuroinformatics research. Most of the resources are free, and many have communities of interest associated with them, allowing researchers to share advice and ideas for use of the data and tools. The new contract is funded by a consortium of NIH Institutes, including NIBIB, and will allow TCG to continue and expand NITRC. Read the full article from TCG.
Grantee News • December 13, 2011
Biomedical researchers at IUPUI’s Purdue School of Engineering and Technology were awarded $400,000 to study a synthetic hydrogel matrix that could potentially trigger both cell proliferation and differentiation. This technique could impact the treatment of Type 1 Diabetes, and bone, cartilage, and other cell deficiencies. Read the full article from Indiana University-Purdue University Indianapolis.
NIBIB in the News • December 1, 2011

Single cell imaging is a growing and interdisciplinary field that requires technical and scientific acumen. The field is an ideal niche for technology-minded scientists. Read the full article from Nature.

Grantee News • December 1, 2011
Surgeons are taught from textbooks which conveniently color-code types of tissues, but that's not what it looks like in real life -- until now. Quyen Nguyen, an NIBIB K08 awardee, demonstrates how a molecular marker can make tumors light up in neon green, showing surgeons exactly where to cut. Read the full article from TEDMED.

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