Creating Biomedical Technologies to Improve Health

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Grantee News • February 21, 2013
Researchers at the University of Pennsylvania have demonstrated that they can outwit the body’s innate immune system to more effectively deliver drugs by identifying a simple peptide that the body recognizes as self and attaching it to a conventional nanoparticle delivery vehicle. This approach could potentially benefit a broad range of biomedical devices that are impacted by immune system attacks, such as pacemakers and other implants. Research findings are described in the journal Science. Read the full article from Science. Watch the video: A "Passport" for the Immune System.
Grantee News • February 19, 2013
NIBIB-funded researchers at Stanford have developed the means to observe brain activity in live mice. Using fluorescent proteins and a microscope implanted in the mouse’s head, scientists were able to correlate activities with brain patterns, and produce a video of the mouse’s brain activity. The system could prove useful in new therapies for neurogenerative diseases such as Alzheimer’s. Research finding were presented in the Feb. 10 online edition of the journal Nature Neuroscience. Read the full article from Stanford.
NIBIB in the News • January 30, 2013
Researchers describe the intricacies of the stem cell niche and their efforts at niche engineering. Rosemarie Hunziker, NIBIB Program Director, speaks to the interdisciplinary nature of this complex task. Read the full article from Nature.
Grantee News • January 29, 2013

NIBIB-funded research offers the convenience, speed, and savings of cloud-based computing, enabling neuroscientists to pay only for the computational power they need, and to scale the computational resources they require to the size of the research challenge at hand. Read the full article from PRWeb.

Science Highlights • January 28, 2013
An NIBIB grantee has developed a dedicated breast CT scanner that allows the breast to be imaged in three dimensions and could help radiologists detect hard-to-find tumors. The scanner uses a radiation dose comparable to standard x-ray mammography and doesn’t require compression of the breast.
Grantee News • January 23, 2013
NIBIB-funded research by multiple teams including Andrea Adamo, Robert Langer, Armon Sharei, Janet Zoldan at the Massachusetts Institute of Technology has yielded a new method to deliver large molecules through a cell membrane using a microfluidic chip. The discovery may lead to new disease treatments, as well as new system for vaccination and is described in the Proceedings of the National Academy of Sciences. Read the full article from Science Daily.
NIBIB in the News • January 14, 2013

In a small study, researchers reported increased healthy tissue growth after surgical repair of damaged cartilage if they put a "hydrogel" scaffolding into the wound to support and nourish the healing process. Read the full article at ScienceDaily.com

Grantee News • January 11, 2013

Research done in collaboration with the NIBIB-funded Center for Biomedical Optical Coherence Tomography Reseach and Translation based at Massachusetts General Hospital, has led to the development of a pill-sized imaging system for the upper gastrointestinal tract. The tethered capsule technique was reported online January 13 in Nature Medicine.

Grantee News • January 9, 2013

Breakthrough research in human cartilage repair by NIBIB grantees Jennifer Elisseeff, Ph.D. at Johns Hopkins University and Garry E. Gold at Stanford University may improve the treatment of cartilage defects. A pilot clinical study demonstrated the efficacy of an adhesive hydrogel biomaterial to support cartilage formation. Magnetic resonance imaging confirmed repair tissue fill, growth, and integration with surrounding cartilage.

Grantee News • December 24, 2012
A new spectroscopy technique developed at an NIBIB-funded research center promises faster and less expensive breast cancer diagnosis. Diffuse reflectance spectroscopy could reduce the rate of inconclusive diagnoses and be used during biopsy procedures, providing accurate results within seconds. Read the full article from Proceedings of the National Academy of Sciences.

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