Grantee News · January 26, 2012
NIBIB researcher Claude Lechene and colleagues report the first use of an approach called multi-isotope imaging spectrometry (MMIS) in living organisms. This technique has outstanding resolution: it provides data in the sub-micrometre range, allowing analysis of structures as small as cellular regions. Read the full article from Nature.
Science Highlights · January 15, 2012
Liver cells from a human donor (primary hepatocytes), human endothelial cells, and mouse fibroblasts are encapsulated together in a polymer skeleton and then implanted in a mouse. The implant forms a so-called human ectopic artificial liver (HEAL). Mice with HEALs are “humanized” because they harbor a human liver in addition to their own liver. HEALs provide insight into human biology, predicting how new drugs might behave in humans. (Figure adapted from PNAS. 2011;108(29):11842–7.)
New drugs are always tested in animals before they are tried in people. However, due to differences in the way that animals and people process drugs in the liver, animal models cannot predict dangerous drug side effects that are unique to humans. To tackle this problem, researchers at the Massachusetts Institute of Technology (MIT) engineered a new mouse model that harbors a tiny human liver. The mouse can be used to study drug safety and efficacy, drug-drug interactions, and human diseases such as hepatitis C.
Press Releases · January 11, 2012
Three new members have been appointed to the National Advisory Council for Biomedical Imaging and Bioengineering (NACBIB) of the National Institute of Biomedical Imaging and Bioengineering (NIBIB).
Science Highlights · December 30, 2011
MRI images for males and females are arranged in order of increasing patient age from 30 to 60.
As the world population ages, the number of people affected with Alzheimer’s disease is rising steadily. While there is yet no cure, certain drugs can slow Alzheimer’s progression, particularly if started early. University of Utah researchers are developing new brain imaging tools that may help doctors diagnose Alzheimer’s much earlier and more accurately than is possible with currently available tests.
Grantee News · December 19, 2011
NITRC currently gives researchers around the world access to software tools and data to advance neuroinformatics research. Most of the resources are free, and many have communities of interest associated with them, allowing researchers to share advice and ideas for use of the data and tools. The new contract is funded by a consortium of NIH Institutes, including NIBIB, and will allow TCG to continue and expand NITRC. Read the full article from TCG.
Grantee News · December 13, 2011
Biomedical researchers at IUPUI’s Purdue School of Engineering and Technology were awarded $400,000 to study a synthetic hydrogel matrix that could potentially trigger both cell proliferation and differentiation. This technique could impact the treatment of Type 1 Diabetes, and bone, cartilage, and other cell deficiencies. Read the full article from Indiana University-Purdue University Indianapolis.
NIBIB in the News · December 1, 2011

Single cell imaging is a growing and interdisciplinary field that requires technical and scientific acumen. The field is an ideal niche for technology-minded scientists. Read the full article from

Grantee News · December 1, 2011
Surgeons are taught from textbooks which conveniently color-code types of tissues, but that's not what it looks like in real life -- until now. Quyen Nguyen, an NIBIB K08 awardee, demonstrates how a molecular marker can make tumors light up in neon green, showing surgeons exactly where to cut. Read the full article from TEDMED.
NIBIB in the News · November 25, 2011
RSNA Image Share Network standardizes the way medical images are shared on the Internet. Discussion of program and future direction with comments by Dr. Pettigrew. Read the full article from ImagingBiz.

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