Grantee News

Grantee News · November 18, 2019
Wearable and implantable devices may allow for intensive self-care for patients with kidney failure outside of the clinic.
Grantee News · November 12, 2019
The researchers genetically engineered CAR T cells with molecular tags, which they were able to monitor in an animal model using position emission tomography (PET) imaging.
Grantee News · November 12, 2019
Electrically stimulating nerves can reduce epileptic seizures, soothe chronic pain, and treat depression. Now, biomedical engineers have made a significant advance that could dramatically reduce the cost of neuromodulation therapy, increase its reliability and make it much less invasive.
Grantee News · October 21, 2019
The National Institutes of Health has awarded $3.4 million to a team of researchers at the University of Virginia and Virginia Tech to develop and produce a “lymph node on a chip.” This tiny, yet sophisticated physical model of the gland will be designed to help researchers better understand the inner workings of the node itself, and, thereby, the broader immune system.

Read more at UVA Today.

Grantee News · October 17, 2019
Mucus is not just a physical barrier that traps bacteria and viruses, but it can also disarm pathogens and prevent them from causing infections. A new study from MIT reveals that glycans — branched sugar molecules found in mucus — are responsible for most of this microbe-taming.

Read more at Science & Technology Research News.

Grantee News · October 9, 2019
MIT engineers designed a drug capsule that can carry insulin or other protein drugs and protect them from the harsh environment of the gastrointestinal tract. When the capsule reaches the small intestine, it breaks down to reveal dissolvable microneedles that attach to the intestinal wall and release drug for uptake into the bloodstream.
Grantee News · October 8, 2019
Biological engineers can program bacteriophages to kill different strains of E. coli by making mutations in the protein that the viruses use to bind to host cells. These engineered phages are less likely to provoke resistance in bacteria, and could help to overcome antibiotic resistance.
Grantee News · October 8, 2019
Anew intubation assist device received the top prize in the Design by Biomedical Undergraduate Teams (DEBUT) challenge, a contest supported by the National Institute of Biomedical Imaging and Bioengineering and the nonprofit VentureWell.

Read more at JAMANetwork.

Grantee News · October 8, 2019
Researchers have developed 3-dimensional human tissue culture models of pediatric and adult brain cancers in a brain-mimicking microenvironment, that includes brain-derived extracellular matrix (ECM) -- the complex network of proteins and amino acids with bound sugars that not only provides support for surrounding neural tissue, but also helps to guide cell growth and development. The development represents a significant advancement for the study of brain tumor biology and pharmacological response.
Grantee News · September 18, 2019
A new ultrasound technique provides a non-invasive way of assessing bone structure on the microscale. Researchers hope to fine-tune the technique for use in assessing osteoporosis risk and treatment.