Science Highlights


Science Highlights · May 14, 2024
AI is applied to CT scans to automatically segment different heart chambers and identify arterial plaque

A collaborative NIH-funded team is using AI to mine common chest CT scans to predict mortality. Their research identified a collection of cardiac factors that were predictive of death in a large group of patients, potentially setting the stage for improved cardiac screening.

Science Highlights · May 9, 2024
A photograph of a mechanoacoustic mouse implant

Measuring heart rate or body temperature may sound easy, but retrieving the data from small animals with bulky traditional tech is difficult, especially during behavioral tests, which are critical for understanding brain disorders. Thanks to a recent study, the animal data is now in reach.

Science Highlights · May 7, 2024
brain receiving ultrasound with microbubbles

Malignant primary brain tumors are the leading cause of cancer deaths among children and young adults with few therapeutic options. A preclinical study in Pharmaceutics shows that combining focused ultrasound with microbubbles opened the blood brain barrier to deliver immunotherapy into the brain of a large animal model.

Science Highlights · April 11, 2024
Artistic representation of a nanoprobe emitting red light

NIBIB-supported researchers have developed a smart nanoprobe designed to infiltrate prostate tumors and send back a signal using an optical imaging technique known as Raman spectroscopy. The new probe, evaluated in mice, has the potential to determine tumor aggressiveness and could also enable sequential monitoring of tumors during therapy to quickly determine if a treatment strategy is working.

Science Highlights · April 5, 2024
innovator with prototype

NIBIB is marking the 10-year anniversary of a commercialization program that helps innovators bring their medical devices from the lab to the marketplace.

Science Highlights · March 28, 2024
A photo of a thin silicon pacemaker device

While pacemakers have treated many patients with heart rhythm disorders, their bulky design and use of wires limits their usefulness and poses a risk of heart damage or infection. Now, researchers have cut the cords, shrunk the size, and expanded the capabilities of current designs.

Science Highlights · March 20, 2024
Photoacoustic imaging of the developing mouse placenta

A multidisciplinary group of NIH-funded scientists have successfully captured real-time, high-resolution images of the developing mouse placenta during the course of pregnancy. Their technique, which combines a surgically implanted window with a next-generation imaging system, provides key insight into placental development under both healthy and pathological conditions.

Science Highlights · March 14, 2024
illustration of red blood vessels

Researchers at The Pennsylvania State University have developed a new synergistic approach to revascularization that combines a new framework made from granular hydrogels with micropuncture, a surgical technique. Their preclinical method could rapidly grow organized blood vessels in live rats.

Science Highlights · March 12, 2024
Image of a dextran-coated gold nanoparticle

Researchers have developed sugar-coated gold nanoparticles to both image and destroy biofilms. In a study, they used the nanoparticles on the teeth and wounded skin of rats and mice, eliminating biofilms in as little as one minute and outperforming common antimicrobials.

Science Highlights · March 7, 2024
bioengineers in lab

In recognition of International Women’s Day (March 8), we’re featuring Rebecca Richards-Kortum, Ph.D., a longtime bioengineer in academia who has contributed globally to improving women's health.