The objective of these funding announcements is to encourage basic, applied, and translational bioengineering research that could make a significant contribution to improving human health. Bioengineering integrates physical, engineering, and computational science principles for the study of biology, medicine, behavior, or health. It advances fundamental concepts, creates knowledge from the molecular to the organ systems level, and develops innovative biologicals, materials, processes, implants, devices, and informatics approaches for the prevention, diagnosis, and treatment of disease, for patient rehabilitation, and for improving health. Some applications are likely to focus on technology development rather than on proving or disproving scientific hypotheses. Bioengineering projects may propose design-directed, developmental, discovery-driven, or hypothesis-driven research. In the case of the Bioengineering Research Grant (BRG) FOAs (PAR-19-158, PAR-19-159) and Bioengineering Research Partnership (BRP) FOAs (PAR-19-156, PAR-19-157), applications will be evaluated against expanded review criteria.
High-risk and early stage development projects are appropriate for all three funding opportunity announcements, especially the Exploratory/Developmental Bioengineering Research Grants (EBRG) PAR-19-149, PAR-19-150. Details of specific interests of individual NIH Institutes and Centers are listed in each of the announcements.