Emphasis:

The emphasis is on the development of biomolecular technologies and associated computational models for biomedical intervention. 

Projects might focus on:

• elucidating important engineering design rules or key foundational principles underlying future engineering, including the use of computational methods
• prototyping or redesigning platform technologies
• characterizing (in vitro, ex vivo, or in vivo) broadly applicable technologies and prototypes

NIBIB interests include but are not limited to: 

• molecular switches for synthetic genetic circuits
• nucleases and genome editors for DNA manipulation and regulation
• engineered viruses and extracellular vesicles for therapeutic agent delivery
• transmembrane CARs for extracellular sensing
• photoactive molecular complexes for optogenetics