Creating Biomedical Technologies to Improve Health


Nuclear Medicine

This program supports the research and development of technologies and techniques that create images out of the gamma-ray or positron (and resulting photon) emissions from radioactive agents that are injected, inhaled, or ingested into the body and then concentrate in specific biological compartments. Active areas supported include the wedding of positron emission tomography (PET) and single photon emission computed tomography (SPECT) to CT and/or to MRI; the design of higher spatial and temporal resolution systems including the compensation of artifacts, improved reconstruction algorithms and the development of new cameras, scintillators and collimators; new approaches to increasing sensitivity and tracking/lowering radiation dose; lower cost and portable systems and kits; and the synthesis and study of targeted radio-labeled molecular probes, particularly multimodal, environmentally-sensitive and switchable agents.