Physiomimetic Materials


This program supports the development and demonstration of broadly applicable physiomimetic materials to enable new paradigms of human health.


The emphasis is on the development of physiomimetic materials and associated computational models for biomedical intervention. 

Projects might focus on:

  • elucidating important engineering design rules or key foundational principles underlying future engineering, including the use of computational methods
  • prototyping or redesigning platform technologies
  • characterizing (in vitro, ex vivo, or in vivo) broadly applicable technologies and prototypes

NIBIB interests include but are not limited to: 

  • electrically conductive and mechano-sensitive scaffolds for repairing tissue
  • photoactive adhesives for surgical sealants
  • biomimetic matrices for T cell activation
  • artificial cells for therapeutic agent delivery