For the NIBIB Trailblazer Award for New and Early Stage Investigators (PAR-20-084), preliminary data are not required, expected, or encouraged. However, if necessary, minimal preliminary data are allowed in support of the feasibility of the research approach. Minimal preliminary data are defined as material which the applicant has independently produced and not yet published in a peer-reviewed journal. For example, unpublished data or data presented in an abstract for a scientific meeting or used in an oral or poster presentation are acceptable. Such evidence, if provided, should only be used to bolster and help establish the foundational premise for the Trailblazer application. All preliminary data should be clearly marked and limited to one-half page which may include one figure. Applications including preliminary data more than one-half page or more than one figure, will be considered noncompliant with the FOA instructions.