Nanoinstrumentation and Force Spectroscopy Publications

Non-ECG-gated cardiac CT angiography in acute stroke is feasible and detects sources of embolism.

Lee PDhillon GPourafkari MDaBreo DJaff ZAppireddy RJin ABoissé Lomax LDurafourt BABoyd JGNasirzadeh ARTampieri DJalini S

Int J Stroke

2023 Aug 22

Advanced Nitric Oxide Generating Nanomedicine for Therapeutic Applications.

Wang ZJin AYang ZHuang W

ACS Nano

2023 May 23

Structural and immunological differences in Plasmodium falciparum sexual stage transmission-blocking vaccines comprised of Pfs25-EPA nanoparticles.

MacDonald NJSingh KReiter KNguyen VShimp RGittis AGChen BBurkhardt MZhang BWang ZHerrera RMoler MLee DYOrr-Gonzalez SHerrod JLambert LERausch KMMuratova OJones DSWu YJin AJGarboczi DNDuffy PENarum DL

NPJ Vaccines

2023 Apr 15

Hydrogen sulfide activatable metal-organic frameworks for Fluorescence Imaging-Guided Photodynamic Therapy of colorectal cancer.

Li HHuang MWei ZHe JMa YLu CJin AWang ZWen L

Front Bioeng Biotechnol

2022

Rational design of semiconducting polymer brushes as cancer theranostics.

Yang ZLi LJin AJHuang WChen X

Mater Horiz

2020 Jun 01

Vesicle Shrinking and Enlargement Play Opposing Roles in the Release of Exocytotic Contents.

Shin WArpino GThiyagarajan SSu RGe LMcDargh ZGuo XWei LShupliakov OJin AO'Shaughnessy BWu LG

Cell Rep

2020 Jan 14

Rational Design of All-Organic Nanoplatform for Highly Efficient MR/NIR-II Imaging-Guided Cancer Phototheranostics.

Hu XChen ZJin AJYang ZGan DWu AAo HHuang WFan Q

Small

2021 Mar

Thrombus Migration and Fragmentation After Intravenous Alteplase Treatment: The INTERRSeCT Study.

Ohara TMenon BKAl-Ajlan FSHorn MNajm MAl-Sultan APuig JDowlatshahi DCalleja Sanz AISohn SIAhn SHPoppe AYMikulik RAsdaghi NField TSJin AAsil TBoulanger JMLetteri FDey SEvans JWGoyal MHill MDAlmekhlafi MDemchuk AM

Stroke

2021 Jan

Wet/Sono-Chemical Synthesis of Enzymatic Two-Dimensional MnO Nanosheets for Synergistic Catalysis-Enhanced Phototheranostics.

Tang WFan WZhang WYang ZLi LWang ZChiang YLLiu YDeng LHe LShen ZJacobson OAronova MAJin AXie JChen X

Adv Mater

2019 May

Polyrotaxane-based supramolecular theranostics.

Yu GYang ZFu XYung BCYang JMao ZShao LHua BLiu YZhang FFan QWang SJacobson OJin AGao CTang XHuang FChen X

Nat Commun

2018 Feb 22

Albumin/vaccine nanocomplexes that assemble in vivo for combination cancer immunotherapy.

Zhu GLynn GMJacobson OChen KLiu YZhang HMa YZhang FTian RNi QCheng SWang ZLu NYung BCWang ZLang LFu XJin AWeiss IDVishwasrao HNiu GShroff HKlinman DMSeder RAChen X

Nat Commun

2017 Dec 05

Intertwining DNA-RNA nanocapsules loaded with tumor neoantigens as synergistic nanovaccines for cancer immunotherapy.

Zhu GMei LVishwasrao HDJacobson OWang ZLiu YYung BCFu XJin ANiu GWang QZhang FShroff HChen X

Nat Commun

2017 Nov 14

Effects of gold nanoparticles on lipid packing and membrane pore formation.

Bhat AEdwards LWFu XBadman DLHuo SJin AJLu Q

Appl Phys Lett

2016 Dec 26

Hierarchical Assembly of Bioactive Amphiphilic Molecule Pairs into Supramolecular Nanofibril Self-Supportive Scaffolds for Stem Cell Differentiation.

Wang ZZhang FWang ZLiu YFu XJin AYung BCChen WFan JYang XNiu GChen X

J Am Chem Soc

2016 Nov 16

Actin dynamics provides membrane tension to merge fusing vesicles into the plasma membrane.

Wen PJGrenklo SArpino GTan XLiao HSHeureaux JPeng SYChiang HCHamid EZhao WDShin WNäreoja TEvergren EJin YKarlsson REbert SNJin ALiu APShupliakov OWu LG

Nat Commun

2016 Aug 31

Clathrin-coat disassembly illuminates the mechanisms of Hsp70 force generation.

Sousa RLiao HSCuéllar JJin SValpuesta JMJin AJLafer EM

Nat Struct Mol Biol

2016 Sep

Self-assembly mechanisms of nanofibers from peptide amphiphiles in solution and on substrate surfaces.

Liao HSLin JLiu YHuang PJin AChen X

Nanoscale

2016 Aug 04

DNA-inorganic hybrid nanovaccine for cancer immunotherapy.

Zhu GLiu YYang XKim YHZhang HJia RLiao HSJin ALin JAronova MLeapman RNie ZNiu GChen X

Nanoscale

2016 Mar 28

Local 3D matrix microenvironment regulates cell migration through spatiotemporal dynamics of contractility-dependent adhesions.

Doyle ADCarvajal NJin AMatsumoto KYamada KM

Nat Commun

2015 Nov 09

Protein-based photothermal theranostics for imaging-guided cancer therapy.

Rong PHuang PLiu ZLin JJin AMa YNiu GYu LZeng WWang WChen X

Nanoscale

2015 Oct 21

Tumor-Specific Formation of Enzyme-Instructed Supramolecular Self-Assemblies as Cancer Theranostics.

Huang PGao YLin JHu HLiao HSYan XTang YJin ASong JNiu GZhang GHorkay FChen X

ACS Nano

2015 Oct 27

Reversible Conformational Change in the Plasmodium falciparum Circumsporozoite Protein Masks Its Adhesion Domains.

Herrera RAnderson CKumar KMolina-Cruz ANguyen VBurkhardt MReiter KShimp RHoward RFSrinivasan PNold MJRagheb DShi LDeCotiis MAebig JLambert LRausch KMMuratova OJin AReed SGSinnis PBarillas-Mury CDuffy PEMacDonald NJNarum DL

Infect Immun

2015 Oct

Polymeric Nanovehicle Regulated Spatiotemporal Real-Time Imaging of the Differentiation Dynamics of Transplanted Neural Stem Cells after Traumatic Brain Injury.

Wang ZWang YWang ZZhao JGutkind JSSrivatsan AZhang GLiao HSFu XJin ATong XNiu GChen X

ACS Nano

2015 Jul 28

Erratum: Post-fusion structural changes and their roles in exocytosis and endocytosis of dense-core vesicles.

Chiang HCShin WZhao WDHamid ESheng JBaydyuk MWen PJJin AMomboisse FWu LG

Nat Commun

2015 Jan 27

Optical and photoacoustic dual-modality imaging guided synergistic photodynamic/photothermal therapies.

Yan XHu HLin JJin AJNiu GZhang SHuang PShen BChen X

Nanoscale

2015 Feb 14

Enhanced fluorescence imaging guided photodynamic therapy of sinoporphyrin sodium loaded graphene oxide.

Yan XNiu GLin JJin AJHu HTang YZhang YWu ALu JZhang SHuang PShen BChen X

Biomaterials

2015 Feb

Early-stage imaging of nanocarrier-enhanced chemotherapy response in living subjects by scalable photoacoustic microscopy.

Nie LHuang PLi WYan XJin AWang ZTang YWang SZhang XNiu GChen X

ACS Nano

2014 Dec 23

Dye-loaded ferritin nanocages for multimodal imaging and photothermal therapy.

Huang PRong PJin AYan XZhang MGLin JHu HWang ZYue XLi WNiu GZeng WWang WZhou KChen X

Adv Mater

2014 Oct 08

Versatile RNA interference nanoplatform for systemic delivery of RNAs.

Choi KYSilvestre OFHuang XMin KHHoward GPHida NJin AJCarvajal NLee SWHong JIChen X

ACS Nano

2014 May 27

Targeted therapeutic nanotubes influence the viscoelasticity of cancer cells to overcome drug resistance.

Bhirde AAChikkaveeraiah BVSrivatsan ANiu GJin AJKapoor AWang ZPatel SPatel VGorbach AMLeapman RDGutkind JSHight Walker ARChen X

ACS Nano

2014 May 27

Post-fusion structural changes and their roles in exocytosis and endocytosis of dense-core vesicles.

Chiang HCShin WZhao WDHamid ESheng JBaydyuk MWen PJJin AMomboisse FWu LG

Nat Commun

2014

Acetylcholinesterase-catalyzed hydrolysis allows ultrasensitive detection of pathogens with the naked eye.

Liu DWang ZJin AHuang XSun XWang FYan QGe SXia NNiu GLiu GHight Walker ARChen X

Angew Chem Int Ed Engl

2013 Dec 23

VEGF-loaded graphene oxide as theranostics for multi-modality imaging-monitored targeting therapeutic angiogenesis of ischemic muscle.

Sun ZHuang PTong GLin JJin ARong PZhu LNie LNiu GCao FChen X

Nanoscale

2013 Aug 07

Gold nanoparticle-based activatable probe for sensing ultralow levels of prostate-specific antigen.

Liu DHuang XWang ZJin ASun XZhu LWang FMa YNiu GHight Walker ARChen X

ACS Nano

2013 Jun 25

Development of a Pfs25-EPA malaria transmission blocking vaccine as a chemically conjugated nanoparticle.

Shimp RLRowe CReiter KChen BNguyen VAebig JRausch KMKumar KWu YJin AJJones DSNarum DL

Vaccine

2013 Jun 19

Unraveling protein-protein interactions in clathrin assemblies via atomic force spectroscopy.

Jin AJLafer EMPeng JQSmith PDNossal R

Methods

2013 Mar

Fabrication of hydrogels with steep stiffness gradients for studying cell mechanical response.

Sunyer RJin AJNossal RSackett DL

PLoS One

2012

A nanoscale graphene oxide-peptide biosensor for real-time specific biomarker detection on the cell surface.

Wang ZHuang PBhirde AJin AMa YNiu GNeamati NChen X

Chem Commun (Camb)

2012 Oct 09

Nuclear mapping of nanodrug delivery systems in dynamic cellular environments.

Bhirde AAKapoor ALiu GIglesias-Bartolome RJin AZhang GXing RLee SLeapman RDGutkind JSChen X

ACS Nano

2012 Jun 26

Analysis of the conformation and function of the Plasmodium falciparum merozoite proteins MTRAP and PTRAMP.

Uchime OHerrera RReiter KKotova SShimp RLMiura KJones DLebowitz JAmbroggio XHurt DEJin AJLong CMiller LHNarum DL

Eukaryot Cell

2012 May

Functional MnO nanoclusters for efficient siRNA delivery.

Xing RLiu GQuan QBhirde AZhang GJin ABryant LHZhang ALiang AEden HSHou YChen X

Chem Commun (Camb)

2011 Nov 28

Enhanced mechanical rigidity of hydrogels formed from enantiomeric peptide assemblies.

Nagy KJGiano MCJin APochan DJSchneider JP

J Am Chem Soc

2011 Sep 28

Combining portable Raman probes with nanotubes for theranostic applications.

Bhirde AALiu GJin AIglesias-Bartolome RSousa AALeapman RDGutkind JSLee SChen X

Theranostics

2011

AFM visualization of clathrin triskelia under fluid and in air.

Kotova SPrasad KSmith PDLafer EMNossal RJin AJ

FEBS Lett

2010 Jan 04

Structure of the Plasmodium falciparum circumsporozoite protein, a leading malaria vaccine candidate.

Plassmeyer MLReiter KShimp RLKotova SSmith PDHurt DEHouse BZou XZhang YHickman MUchime OHerrera RNguyen VGlen JLebowitz JJin AJMiller LHMacDonald NJWu YNarum DL

J Biol Chem

2009 Sep 25

Characterization of a protective Escherichia coli-expressed Plasmodium falciparum merozoite surface protein 3 indicates a non-linear, multi-domain structure.

Tsai CWDuggan PFJin AJMacdonald NJKotova SLebowitz JHurt DEShimp RLLambert LMiller LHLong CASaul ANarum DL

Mol Biochem Parasitol

2009 Mar

A Mycobacterium tuberculosis-derived lipid inhibits membrane fusion by modulating lipid membrane domains.

Hayakawa ETokumasu FNardone GAJin AJHackley VADvorak JA

Biophys J

2007 Dec 01

Measuring the elasticity of clathrin-coated vesicles via atomic force microscopy.

Jin AJPrasad KSmith PDLafer EMNossal R